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Pathway Interaction Database homepage

Retirement notice

PID data are now available for the research community via the NDEx database, hosted by the Ideker Lab at the UC San Diego School of Medicine. To access PID files click “start now” and on the public server welcome page type nci in the search box. NDEx will return all the PID network files. PID data is also available for download in BioPax format on GitHub. The NCI PID data portal will be retired on or around December 31, 2015. If you have any questions, please contact the NCI CBIIT Application Support team.

Pathway Interaction Database

Biomolecular interactions and cellular processes assembled into authoritative human signaling pathways

136 Human Pathways 9248 Interactions Curated by NCI-Nature up to September 2012

322 Human Pathways 7575 Interactions Imported from BioCarta/Reactome

Date last updated: 18 September 2012


Simple search help

You may enter molecule names, molecule IDs, biological process terms and/or biological process IDs as a comma-separated list. Molecule names may be any alias listed in Entrez Gene. Molecule IDs may be UniProt protein accession numbers, HUGO gene symbols, Entrez Gene IDs, and CAS numbers. Biological processes may be Gene Ontology (GO) terms, GO identifiers (entered in the format GO:0000000), and NCI thesaurus terms and identifiers.

Wildcard searches can be performed with search terms of 3 or more characters using the asterisk (*). For example, “Ras*” will find, among other terms, “Ras family”. Asterisks can be included at the beginning, end or both beginning and end of the term.

See the User guide for more information

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