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NCI-Nature curated

Pathway Source
ALK1 pathway NCI-Nature curated
AP-1 transcription factor network NCI-Nature curated
ATF-2 transcription factor network NCI-Nature curated
ATM pathway NCI-Nature curated
ATR signaling pathway NCI-Nature curated
Alpha-synuclein signaling NCI-Nature curated
Alternative NF-kappaB pathway NCI-Nature curated
Androgen-mediated signaling NCI-Nature curated
Angiopoietin receptor Tie2-mediated signaling NCI-Nature curated
Arf1 pathway NCI-Nature curated
Arf6 signaling events NCI-Nature curated
    Subnetwork: Arf6 trafficking events
NCI-Nature curated
Atypical NF-kappaB pathway NCI-Nature curated
BARD1 signaling events NCI-Nature curated
BCR signaling pathway NCI-Nature curated
BMP receptor signaling NCI-Nature curated
C-MYB transcription factor network NCI-Nature curated
C-MYC pathway NCI-Nature curated
CD40/CD40L signaling NCI-Nature curated
CXCR3-mediated signaling events NCI-Nature curated
CXCR4-mediated signaling events NCI-Nature curated
Canonical NF-kappaB pathway NCI-Nature curated
Caspase Cascade in Apoptosis NCI-Nature curated
Cellular roles of Anthrax toxin NCI-Nature curated
Ceramide signaling pathway NCI-Nature curated
Circadian rhythm pathway NCI-Nature curated
Class I PI3K signaling events NCI-Nature curated
DNA-PK pathway in nonhomologous end joining NCI-Nature curated
E-cadherin signaling events NCI-Nature curated
E2F transcription factor network NCI-Nature curated
EGF receptor (ErbB1) signaling pathway NCI-Nature curated
EPO signaling pathway NCI-Nature curated
Effects of Botulinum toxin NCI-Nature curated
Endogenous TLR signaling NCI-Nature curated
Endothelins NCI-Nature curated
EphrinA-EPHA pathway NCI-Nature curated
    Subnetwork: Ephrin A reverse signaling
NCI-Nature curated
EphrinB-EPHB pathway NCI-Nature curated
ErbB receptor signaling network NCI-Nature curated
ErbB2/ErbB3 signaling events NCI-Nature curated
ErbB4 signaling events NCI-Nature curated
FAS (CD95) signaling pathway NCI-Nature curated
FGF signaling pathway NCI-Nature curated
FOXA transcription factor networks NCI-Nature curated
FOXM1 transcription factor network NCI-Nature curated
Fanconi anemia pathway NCI-Nature curated
Fc-epsilon receptor I signaling in mast cells NCI-Nature curated
FoxO family signaling NCI-Nature curated
GMCSF-mediated signaling events NCI-Nature curated
Glucocorticoid receptor signaling NCI-Nature curated
Glypican pathway NCI-Nature curated
    Subnetwork: Glypican 1 network
NCI-Nature curated
HIF-2-alpha transcription factor network NCI-Nature curated
HIV-1 Nef: Negative effector of Fas and TNF-alpha NCI-Nature curated
Hypoxic and oxygen homeostasis regulation of HIF-1-alpha NCI-Nature curated
IFN-gamma pathway NCI-Nature curated
IGF1 pathway NCI-Nature curated
IL1-mediated signaling events NCI-Nature curated
IL12-mediated signaling events NCI-Nature curated
IL2-mediated signaling events NCI-Nature curated
IL23-mediated signaling events NCI-Nature curated
IL27-mediated signaling events NCI-Nature curated
IL3-mediated signaling events NCI-Nature curated
IL4-mediated signaling events NCI-Nature curated
IL5-mediated signaling events NCI-Nature curated
IL6-mediated signaling events NCI-Nature curated
IL8-mediated signaling events NCI-Nature curated
Insulin Pathway NCI-Nature curated
Integrin family cell surface interactions NCI-Nature curated
    Subnetwork: AlphaE beta7 integrin cell surface interactions
NCI-Nature curated
    Subnetwork: Beta1 integrin cell surface interactions
NCI-Nature curated
    Subnetwork: Beta3 integrin cell surface interactions
NCI-Nature curated
Integrin-linked kinase signaling NCI-Nature curated
Integrins in angiogenesis NCI-Nature curated
LKB1 signaling events NCI-Nature curated
LPA receptor mediated events NCI-Nature curated
    Subnetwork: LPA4-mediated signaling events
NCI-Nature curated
Lissencephaly gene (LIS1) in neuronal migration and development NCI-Nature curated
N-cadherin signaling events NCI-Nature curated
Nectin adhesion pathway NCI-Nature curated
Nephrin/Neph1 signaling in the kidney podocyte NCI-Nature curated
Netrin-mediated signaling events NCI-Nature curated
Neurotrophic factor-mediated Trk receptor signaling NCI-Nature curated
Notch signaling pathway NCI-Nature curated
PDGF receptor signaling network NCI-Nature curated
PDGFR-alpha signaling pathway NCI-Nature curated
PDGFR-beta signaling pathway NCI-Nature curated
Plasma membrane estrogen receptor signaling NCI-Nature curated
Plexin-D1 Signaling NCI-Nature curated
Polo-like kinase signaling events in the cell cycle NCI-Nature curated
Posttranslational regulation of adherens junction stability and dissassembly NCI-Nature curated
Presenilin action in Notch and Wnt signaling NCI-Nature curated
Proteoglycan syndecan-mediated signaling events NCI-Nature curated
Reelin signaling pathway NCI-Nature curated
Regulation of CDC42 activity NCI-Nature curated
    Subnetwork: CDC42 signaling events
NCI-Nature curated
Regulation of RAC1 activity NCI-Nature curated
Regulation of Ras family activation NCI-Nature curated
Regulation of RhoA activity NCI-Nature curated
    Subnetwork: RhoA signaling pathway
NCI-Nature curated
Regulation of Telomerase NCI-Nature curated
Regulation of cytoplasmic and nuclear SMAD2/3 signaling NCI-Nature curated
Regulation of nuclear beta catenin signaling and target gene transcription NCI-Nature curated
Regulation of retinoblastoma protein NCI-Nature curated
Retinoic acid receptors-mediated signaling NCI-Nature curated
Role of Calcineurin-dependent NFAT signaling in lymphocytes NCI-Nature curated
SHP2 signaling NCI-Nature curated
Signaling by Aurora kinases NCI-Nature curated
    Subnetwork: Aurora B signaling
NCI-Nature curated
    Subnetwork: Aurora C signaling
NCI-Nature curated
Signaling events mediated by HDAC Class I NCI-Nature curated
Signaling events mediated by HDAC Class II NCI-Nature curated
Signaling events mediated by HDAC Class III NCI-Nature curated
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) NCI-Nature curated
Signaling events mediated by PRL NCI-Nature curated
Signaling events mediated by PTP1B NCI-Nature curated
Signaling events mediated by Stem cell factor receptor (c-Kit) NCI-Nature curated
Signaling events mediated by TCPTP NCI-Nature curated
Signaling events mediated by VEGFR1 and VEGFR2 NCI-Nature curated
Signaling events mediated by focal adhesion kinase NCI-Nature curated
Signaling events mediated by the Hedgehog family NCI-Nature curated
Signaling events regulated by Ret tyrosine kinase NCI-Nature curated
Sphingosine 1-phosphate (S1P) pathway NCI-Nature curated
Sumoylation by RanBP2 regulates transcriptional repression NCI-Nature curated
TCR signaling in naïve CD4+ T cells NCI-Nature curated
TCR signaling in naïve CD8+ T cells NCI-Nature curated
TGF-beta receptor signaling NCI-Nature curated
TNF receptor signaling pathway NCI-Nature curated
TRAIL signaling pathway NCI-Nature curated
Thrombin/protease-activated receptor (PAR) pathway NCI-Nature curated
Thromboxane A2 receptor signaling NCI-Nature curated
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling NCI-Nature curated
VEGF and VEGFR signaling network NCI-Nature curated
VEGFR3 signaling in lymphatic endothelium NCI-Nature curated
Validated nuclear estrogen receptor alpha network NCI-Nature curated
Validated nuclear estrogen receptor beta network NCI-Nature curated
Visual signal transduction: Cones NCI-Nature curated
Visual signal transduction: Rods NCI-Nature curated
Wnt signaling network NCI-Nature curated
    Subnetwork: Canonical Wnt signaling pathway
NCI-Nature curated
    Subnetwork: Degradation of beta catenin
NCI-Nature curated
    Subnetwork: Noncanonical Wnt signaling pathway
NCI-Nature curated
a4b7 Integrin signaling NCI-Nature curated
a6b1 and a6b4 Integrin signaling NCI-Nature curated
amb2 Integrin signaling NCI-Nature curated
mTOR signaling pathway NCI-Nature curated
p38 MAPK signaling pathway NCI-Nature curated
    Subnetwork: Regulation of p38-alpha and p38-beta
NCI-Nature curated
p53 pathway NCI-Nature curated
p63 transcription factor network NCI-Nature curated
p73 transcription factor network NCI-Nature curated
p75(NTR)-mediated signaling NCI-Nature curated

BioCarta

Pathway Source
ß-arrestins in gpcr desensitization BioCarta Imported
acetylation and deacetylation of rela in nucleus BioCarta Imported
actions of nitric oxide in the heart BioCarta Imported
activation of camp-dependent protein kinase pka BioCarta Imported
activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor BioCarta Imported
activation of pkc through g-protein coupled receptors BioCarta Imported
adp-ribosylation factor BioCarta Imported
agrin in postsynaptic differentiation BioCarta Imported
ahr signal transduction pathway BioCarta Imported
akap95 role in mitosis and chromosome dynamics BioCarta Imported
akt signaling pathway BioCarta Imported
alk in cardiac myocytes BioCarta Imported
alpha-synuclein and parkin-mediated proteolysis in parkinson`s disease BioCarta Imported
alternative complement pathway BioCarta Imported
angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling BioCarta Imported
anthrax toxin mechanism of action BioCarta Imported
antigen processing and presentation BioCarta Imported
antisense pathway BioCarta Imported
apoptotic dna-fragmentation and tissue homeostasis BioCarta Imported
apoptotic signaling in response to dna damage BioCarta Imported
aspirin blocks signaling pathway involved in platelet activation BioCarta Imported
atm signaling pathway BioCarta Imported
attenuation of gpcr signaling BioCarta Imported
b cell survival pathway BioCarta Imported
basic mechanism of action of ppara pparb(d) and pparg and effects on gene expression BioCarta Imported
basic mechanisms of sumoylation BioCarta Imported
bcr signaling pathway BioCarta Imported
bioactive peptide induced signaling pathway BioCarta Imported
bone remodeling BioCarta Imported
brca1 dependent ub ligase activity BioCarta Imported
btg family proteins and cell cycle regulation BioCarta Imported
ca-calmodulin-dependent protein kinase activation BioCarta Imported
cadmium induces dna synthesis and proliferation in macrophages BioCarta Imported
calcium signaling by hbx of hepatitis b virus BioCarta Imported
cardiac protection against ros BioCarta Imported
carm1 and regulation of the estrogen receptor BioCarta Imported
caspase cascade in apoptosis BioCarta Imported
cbl mediated ligand-induced downregulation of egf receptors pathway BioCarta Imported
ccr3 signaling in eosinophils BioCarta Imported
cd40l signaling pathway BioCarta Imported
cdc25 and chk1 regulatory pathway in response to dna damage BioCarta Imported
cdk regulation of dna replication BioCarta Imported
cell cycle: g1/s check point BioCarta Imported
cell cycle: g2/m checkpoint BioCarta Imported
cell to cell adhesion signaling BioCarta Imported
ceramide signaling pathway BioCarta Imported
chaperones modulate interferon signaling pathway BioCarta Imported
chrebp regulation by carbohydrates and camp BioCarta Imported
chromatin remodeling by hswi/snf atp-dependent complexes BioCarta Imported
classical complement pathway BioCarta Imported
control of gene expression by vitamin d receptor BioCarta Imported
control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk) BioCarta Imported
corticosteroids and cardioprotection BioCarta Imported
ctcf: first multivalent nuclear factor BioCarta Imported
cxcr4 signaling pathway BioCarta Imported
cyclin e destruction pathway BioCarta Imported
cycling of ran in nucleocytoplasmic transport BioCarta Imported
cyclins and cell cycle regulation BioCarta Imported
cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway BioCarta Imported
d4gdi signaling pathway BioCarta Imported
degradation of the rar and rxr by the proteasome BioCarta Imported
deregulation of cdk5 in alzheimers disease BioCarta Imported
dicer pathway BioCarta Imported
double stranded rna induced gene expression BioCarta Imported
downregulated of mta-3 in er-negative breast tumors BioCarta Imported
e2f1 destruction pathway BioCarta Imported
effects of calcineurin in keratinocyte differentiation BioCarta Imported
egf signaling pathway BioCarta Imported
eicosanoid metabolism BioCarta Imported
endocytotic role of ndk phosphins and dynamin BioCarta Imported
epo signaling pathway BioCarta Imported
er associated degradation (erad) pathway BioCarta Imported
erk and pi-3 kinase are necessary for collagen binding in corneal epithelia BioCarta Imported
erk1/erk2 mapk signaling pathway BioCarta Imported
erythropoietin mediated neuroprotection through nf-kb BioCarta Imported
estrogen responsive protein efp controls cell cycle and breast tumors growth BioCarta Imported
eukaryotic protein translation BioCarta Imported
extrinsic prothrombin activation pathway BioCarta Imported
fas signaling pathway (cd95) BioCarta Imported
fc epsilon receptor i signaling in mast cells BioCarta Imported
fibrinolysis pathway BioCarta Imported
fmlp induced chemokine gene expression in hmc-1 cells BioCarta Imported
fosb gene expression and drug abuse BioCarta Imported
g-protein signaling through tubby proteins BioCarta Imported
g-secretase mediated erbb4 signaling pathway BioCarta Imported
gamma-aminobutyric acid receptor life cycle pathway BioCarta Imported
gata3 participate in activating the th2 cytokine genes expression BioCarta Imported
generation of amyloid b-peptide by ps1 BioCarta Imported
granzyme a mediated apoptosis pathway BioCarta Imported
growth hormone signaling pathway BioCarta Imported
hemoglobins chaperone BioCarta Imported
hiv-1 defeats host-mediated resistance by cem15 BioCarta Imported
hiv-1 nef: negative effector of fas and tnf BioCarta Imported
hop pathway in cardiac development BioCarta Imported
how does salmonella hijack a cell BioCarta Imported
how progesterone initiates the oocyte maturation BioCarta Imported
human cytomegalovirus and map kinase pathways BioCarta Imported
hypoxia and p53 in the cardiovascular system BioCarta Imported
hypoxia-inducible factor in the cardivascular system BioCarta Imported
ifn alpha signaling pathway BioCarta Imported
ifn gamma signaling pathway BioCarta Imported
igf-1 signaling pathway BioCarta Imported
il 2 signaling pathway BioCarta Imported
il 3 signaling pathway BioCarta Imported
il 4 signaling pathway BioCarta Imported
il 6 signaling pathway BioCarta Imported
il-10 anti-inflammatory signaling pathway BioCarta Imported
il-2 receptor beta chain in t cell activation BioCarta Imported
il-7 signal transduction BioCarta Imported
il12 and stat4 dependent signaling pathway in th1 development BioCarta Imported
il22 soluble receptor signaling pathway BioCarta Imported
inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages BioCarta Imported
induction of apoptosis through dr3 and dr4/5 death receptors BioCarta Imported
influence of ras and rho proteins on g1 to s transition BioCarta Imported
inhibition of cellular proliferation by gleevec BioCarta Imported
inhibition of huntingtons disease neurodegeneration by histone deacetylase inhibitors BioCarta Imported
inhibition of matrix metalloproteinases BioCarta Imported
insulin signaling pathway BioCarta Imported
integrin signaling pathway BioCarta Imported
internal ribosome entry pathway BioCarta Imported
intrinsic prothrombin activation pathway BioCarta Imported
ion channels and their functional role in vascular endothelium BioCarta Imported
ionomycin and phorbal ester signaling pathway BioCarta Imported
keratinocyte differentiation BioCarta Imported
lck and fyn tyrosine kinases in initiation of tcr activation BioCarta Imported
lectin induced complement pathway BioCarta Imported
links between pyk2 and map kinases BioCarta Imported
lissencephaly gene (lis1) in neuronal migration and development BioCarta Imported
map kinase inactivation of smrt corepressor BioCarta Imported
mapkinase signaling pathway BioCarta Imported
mcalpain and friends in cell motility BioCarta Imported
mechanism of acetaminophen activity and toxicity BioCarta Imported
mechanism of gene regulation by peroxisome proliferators via ppara BioCarta Imported
mechanism of protein import into the nucleus BioCarta Imported
mechanisms of transcriptional repression by dna methylation BioCarta Imported
melanocyte development and pigmentation pathway BioCarta Imported
metabolism of anandamide an endogenous cannabinoid BioCarta Imported
mets affect on macrophage differentiation BioCarta Imported
mtor signaling pathway BioCarta Imported
multi-drug resistance factors BioCarta Imported
multi-step regulation of transcription by pitx2 BioCarta Imported
multiple antiapoptotic pathways from igf-1r signaling lead to bad phosphorylation BioCarta Imported
nerve growth factor pathway (ngf) BioCarta Imported
neuroregulin receptor degredation protein-1 controls erbb3 receptor recycling BioCarta Imported
nf-kb signaling pathway BioCarta Imported
nfat and hypertrophy of the heart BioCarta Imported
nfkb activation by nontypeable hemophilus influenzae BioCarta Imported
nitric oxide signaling pathway BioCarta Imported
no2-dependent il-12 pathway in nk cells BioCarta Imported
nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells BioCarta Imported
opposing roles of aif in apoptosis and cell survival BioCarta Imported
overview of telomerase protein component gene htert transcriptional regulation BioCarta Imported
overview of telomerase rna component gene hterc transcriptional regulation BioCarta Imported
oxidative stress induced gene expression via nrf2 BioCarta Imported
p38 mapk signaling pathway BioCarta Imported
p53 signaling pathway BioCarta Imported
pdgf signaling pathway BioCarta Imported
pelp1 modulation of estrogen receptor activity BioCarta Imported
pertussis toxin-insensitive ccr5 signaling in macrophage BioCarta Imported
phosphatidylcholine biosynthesis pathway BioCarta Imported
phosphoinositides and their downstream targets BioCarta Imported
phospholipase c delta in phospholipid associated cell signaling BioCarta Imported
phospholipase c signaling pathway BioCarta Imported
phospholipase c-epsilon pathway BioCarta Imported
phospholipids as signalling intermediaries BioCarta Imported
phosphorylation of mek1 by cdk5/p35 down regulates the map kinase pathway BioCarta Imported
pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase BioCarta Imported
platelet amyloid precursor protein pathway BioCarta Imported
polyadenylation of mrna BioCarta Imported
prion pathway BioCarta Imported
proteasome complex BioCarta Imported
protein kinase a at the centrosome BioCarta Imported
proteolysis and signaling pathway of notch BioCarta Imported
pten dependent cell cycle arrest and apoptosis BioCarta Imported
rac1 cell motility signaling pathway BioCarta Imported
ras signaling pathway BioCarta Imported
ras-independent pathway in nk cell-mediated cytotoxicity BioCarta Imported
rb tumor suppressor/checkpoint signaling in response to dna damage BioCarta Imported
regulation of bad phosphorylation BioCarta Imported
regulation of cell cycle progression by plk3 BioCarta Imported
regulation of ck1/cdk5 by type 1 glutamate receptors BioCarta Imported
regulation of eif-4e and p70s6 kinase BioCarta Imported
regulation of eif2 BioCarta Imported
regulation of map kinase pathways through dual specificity phosphatases BioCarta Imported
regulation of p27 phosphorylation during cell cycle progression BioCarta Imported
regulation of pgc-1a BioCarta Imported
regulation of spermatogenesis by crem BioCarta Imported
regulation of splicing through sam68 BioCarta Imported
regulation of transcriptional activity by pml BioCarta Imported
regulators of bone mineralization BioCarta Imported
repression of pain sensation by the transcriptional regulator dream BioCarta Imported
reversal of insulin resistance by leptin BioCarta Imported
rho cell motility signaling pathway BioCarta Imported
rho-selective guanine exchange factor akap13 mediates stress fiber formation BioCarta Imported
rna polymerase iii transcription BioCarta Imported
role of ß-arrestins in the activation and targeting of map kinases BioCarta Imported
role of brca1 brca2 and atr in cancer susceptibility BioCarta Imported
role of egf receptor transactivation by gpcrs in cardiac hypertrophy BioCarta Imported
role of erbb2 in signal transduction and oncology BioCarta Imported
role of erk5 in neuronal survival pathway BioCarta Imported
role of mal in rho-mediated activation of srf BioCarta Imported
role of mef2d in t-cell apoptosis BioCarta Imported
role of mitochondria in apoptotic signaling BioCarta Imported
role of nicotinic acetylcholine receptors in the regulation of apoptosis BioCarta Imported
role of parkin in ubiquitin-proteasomal pathway BioCarta Imported
role of pi3k subunit p85 in regulation of actin organization and cell migration BioCarta Imported
role of ppar-gamma coactivators in obesity and thermogenesis BioCarta Imported
role of ran in mitotic spindle regulation BioCarta Imported
roles of ß arrestin dependent recruitment of src kinases in gpcr signaling BioCarta Imported
segmentation clock BioCarta Imported
signal dependent regulation of myogenesis by corepressor mitr BioCarta Imported
signal transduction through il1r BioCarta Imported
signaling pathway from g-protein families BioCarta Imported
skeletal muscle hypertrophy is regulated via akt-mtor pathway BioCarta Imported
sodd/tnfr1 signaling pathway BioCarta Imported
sonic hedgehog receptor ptc1 regulates cell cycle BioCarta Imported
spliceosomal assembly BioCarta Imported
sprouty regulation of tyrosine kinase signals BioCarta Imported
srebp control of lipid synthesis BioCarta Imported
stat3 signaling pathway BioCarta Imported
stathmin and breast cancer resistance to antimicrotubule agents BioCarta Imported
stress induction of hsp regulation BioCarta Imported
sumoylation as a mechanism to modulate ctbp-dependent gene responses BioCarta Imported
sumoylation by ranbp2 regulates transcriptional repression BioCarta Imported
t cell receptor signaling pathway BioCarta Imported
telomeres telomerase cellular aging and immortality BioCarta Imported
tgf beta signaling pathway BioCarta Imported
the 41bb-dependent immune response BioCarta Imported
the co-stimulatory signal during t-cell activation BioCarta Imported
the igf-1 receptor and longevity BioCarta Imported
the information processing pathway at the ifn beta enhancer BioCarta Imported
the prc2 complex sets long-term gene silencing through modification of histone tails BioCarta Imported
thrombin signaling and protease-activated receptors BioCarta Imported
tnf/stress related signaling BioCarta Imported
tnfr1 signaling pathway BioCarta Imported
tnfr2 signaling pathway BioCarta Imported
toll-like receptor pathway BioCarta Imported
tpo signaling pathway BioCarta Imported
transcription factor creb and its extracellular signals BioCarta Imported
transcription regulation by methyltransferase of carm1 BioCarta Imported
transcriptional activation of dbpb from mrna BioCarta Imported
trefoil factors initiate mucosal healing BioCarta Imported
trka receptor signaling pathway BioCarta Imported
tsp-1 induced apoptosis in microvascular endothelial cell BioCarta Imported
tumor suppressor arf inhibits ribosomal biogenesis BioCarta Imported
ucalpain and friends in cell spread BioCarta Imported
vegf hypoxia and angiogenesis BioCarta Imported
visceral fat deposits and the metabolic syndrome BioCarta Imported
visual signal transduction BioCarta Imported
west nile virus BioCarta Imported
wnt lrp6 signalling BioCarta Imported
wnt signaling pathway BioCarta Imported
y branching of actin filaments BioCarta Imported
yaci and bcma stimulation of b cell immune responses BioCarta Imported

Reactome

Pathway Source
3' -UTR-mediated translational regulation Reactome Imported
3' -UTR-mediated translational regulation Reactome Imported
    Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression
Reactome Imported
APC-Cdc20 mediated degradation of Nek2A Reactome Imported
Activated AMPK stimulates fatty-acid oxidation in muscle Reactome Imported
    Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix
Reactome Imported
Amine compound SLC transporters Reactome Imported
    Subnetwork: Na+/Cl- dependent neurotransmitter transporters
Reactome Imported
    Subnetwork: Rhesus glycoproteins mediate ammonium transport.
Reactome Imported
Amino acid and oligopeptide SLC transporters Reactome Imported
    Subnetwork: Amino acid transport across the plasma membrane
Reactome Imported
    Subnetwork: Organic anion transporters
Reactome Imported
    Subnetwork: Proton-coupled neutral amino acid transporters
Reactome Imported
    Subnetwork: Proton/oligonucleotide cotransporters
Reactome Imported
Apoptosis Reactome Imported
    Subnetwork: Activation and oligomerization of BAK protein
Reactome Imported
    Subnetwork: Activation of BAD and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of BH3-only proteins
Reactome Imported
    Subnetwork: Activation of BIM and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of BMF and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of DNA fragmentation factor
Reactome Imported
    Subnetwork: Activation of NOXA and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of PUMA and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of Pro-Caspase 8
Reactome Imported
    Subnetwork: Activation of caspases through apoptosome-mediated cleavage
Reactome Imported
    Subnetwork: Activation, myristolyation of BID and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation, translocation and oligomerization of BAX
Reactome Imported
    Subnetwork: Apoptosis induced DNA fragmentation
Reactome Imported
    Subnetwork: Apoptotic cleavage of cell adhesion proteins
Reactome Imported
    Subnetwork: Apoptotic cleavage of cellular proteins
Reactome Imported
    Subnetwork: Apoptotic execution phase
Reactome Imported
    Subnetwork: Apoptotic factor-mediated response
Reactome Imported
    Subnetwork: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Reactome Imported
    Subnetwork: Breakdown of the nuclear lamina
Reactome Imported
    Subnetwork: Caspase-8 is formed from procaspase-8
Reactome Imported
    Subnetwork: Caspase-mediated cleavage of cytoskeletal proteins
Reactome Imported
    Subnetwork: Cytochrome c-mediated apoptotic response
Reactome Imported
    Subnetwork: Death Receptor Signalling
Reactome Imported
    Subnetwork: Extrinsic Pathway for Apoptosis
Reactome Imported
    Subnetwork: FasL/ CD95L signaling
Reactome Imported
    Subnetwork: Formation of apoptosome
Reactome Imported
    Subnetwork: Intrinsic Pathway for Apoptosis
Reactome Imported
    Subnetwork: Regulation of Apoptosis
Reactome Imported
    Subnetwork: Regulation of PAK-2p34 activity by PS-GAP/RHG10
Reactome Imported
    Subnetwork: Regulation of activated PAK-2p34 by proteasome mediated degradation
Reactome Imported
    Subnetwork: Release of apoptotic factors from the mitochondria
Reactome Imported
    Subnetwork: Role of DCC in regulating apoptosis
Reactome Imported
    Subnetwork: SMAC binds to IAPs
Reactome Imported
    Subnetwork: SMAC-mediated apoptotic response
Reactome Imported
    Subnetwork: SMAC-mediated dissociation of IAP:caspase complexes
Reactome Imported
    Subnetwork: Stimulation of the cell death response by PAK-2p34
Reactome Imported
    Subnetwork: TNF signaling
Reactome Imported
    Subnetwork: TRAIL signaling
Reactome Imported
Axon guidance Reactome Imported
    Subnetwork: Activation of Rac
Reactome Imported
    Subnetwork: CHL1 interactions
Reactome Imported
    Subnetwork: CRMPs in Sema3A signaling
Reactome Imported
    Subnetwork: DCC mediated attractive signaling
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: Inactivation of Cdc42 and Rac
Reactome Imported
    Subnetwork: Interaction between L1 and Ankyrins
Reactome Imported
    Subnetwork: L1CAM interactions
Reactome Imported
    Subnetwork: MAP kinase cascade
Reactome Imported
    Subnetwork: MEK activation
Reactome Imported
    Subnetwork: NCAM signaling for neurite out-growth
Reactome Imported
    Subnetwork: NCAM1 interactions
Reactome Imported
    Subnetwork: Netrin mediated repulsion signals
Reactome Imported
    Subnetwork: Netrin-1 signaling
Reactome Imported
    Subnetwork: Neurofascin interactions
Reactome Imported
    Subnetwork: NrCAM interactions
Reactome Imported
    Subnetwork: Other semaphorin interactions
Reactome Imported
    Subnetwork: RAF activation
Reactome Imported
    Subnetwork: RAF phosphorylates MEK
Reactome Imported
    Subnetwork: Recycling pathway of L1
Reactome Imported
    Subnetwork: Regulation of Commissural axon pathfinding by Slit and Robo
Reactome Imported
    Subnetwork: Role of Abl in Robo-Slit signaling
Reactome Imported
    Subnetwork: Role of second messengers in netrin-1 signaling
Reactome Imported
    Subnetwork: SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
Reactome Imported
    Subnetwork: Sema3A PAK dependent Axon repulsion
Reactome Imported
    Subnetwork: Sema4D in semaphorin signaling
Reactome Imported
    Subnetwork: Sema4D induced cell migration and growth-cone collapse
Reactome Imported
    Subnetwork: Sema4D mediated inhibition of cell attachment and migration
Reactome Imported
    Subnetwork: Semaphorin interactions
Reactome Imported
    Subnetwork: Signal transduction by L1
Reactome Imported
    Subnetwork: Signaling by Robo receptor
Reactome Imported
Bile salt and organic anion SLC transporters Reactome Imported
    Subnetwork: Proton-coupled monocarboxylate transport
Reactome Imported
    Subnetwork: Sodium-coupled sulphate, di- and tri-carboxylate transporters
Reactome Imported
Biological oxidations Reactome Imported
    Subnetwork: Acetylation
Reactome Imported
    Subnetwork: Amine Oxidase reactions
Reactome Imported
    Subnetwork: Amino Acid conjugation
Reactome Imported
    Subnetwork: Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Reactome Imported
    Subnetwork: COX reactions
Reactome Imported
    Subnetwork: CYP2E1 reactions
Reactome Imported
    Subnetwork: Conjugation of benzoate with glycine
Reactome Imported
    Subnetwork: Conjugation of carboxylic acids
Reactome Imported
    Subnetwork: Conjugation of phenylacetate with glutamine
Reactome Imported
    Subnetwork: Conjugation of salicylate with glycine
Reactome Imported
    Subnetwork: Cytochrome P450 - arranged by substrate type
Reactome Imported
    Subnetwork: Cytosolic sulfonation of small molecules
Reactome Imported
    Subnetwork: Eicosanoids
Reactome Imported
    Subnetwork: Endogenous sterols
Reactome Imported
    Subnetwork: Ethanol oxidation
Reactome Imported
    Subnetwork: FMO oxidizes nucleophiles
Reactome Imported
    Subnetwork: Fatty acids
Reactome Imported
    Subnetwork: Formation of PAPS
Reactome Imported
    Subnetwork: Formation of the active cofactor, UDP-glucuronate
Reactome Imported
    Subnetwork: Glucuronidation
Reactome Imported
    Subnetwork: Glutathione conjugation
Reactome Imported
    Subnetwork: Glutathione synthesis
Reactome Imported
    Subnetwork: Methylation
Reactome Imported
    Subnetwork: Miscellaneous substrates
Reactome Imported
    Subnetwork: Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2
Reactome Imported
    Subnetwork: Phase 1 - Functionalization of compounds
Reactome Imported
    Subnetwork: Phase II conjugation
Reactome Imported
    Subnetwork: Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs
Reactome Imported
    Subnetwork: Sterols are 12-hydroxylated by CYP8B1
Reactome Imported
    Subnetwork: Vitamins
Reactome Imported
    Subnetwork: Xenobiotics
Reactome Imported
Botulinum neurotoxicity Reactome Imported
    Subnetwork: BoNT Light Chain Types A, C1, E cleave SNAP-25
Reactome Imported
    Subnetwork: BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin
Reactome Imported
    Subnetwork: Proteolytic cleavage of SNARE complex proteins
Reactome Imported
    Subnetwork: Translocation of BoNT Light chain
Reactome Imported
Cdc20:Phospho-APC/C mediated degradation of Cyclin A Reactome Imported
Cell Cycle Checkpoints Reactome Imported
    Subnetwork: Activation of ATR in response to replication stress
Reactome Imported
    Subnetwork: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Reactome Imported
    Subnetwork: Amplification of signal from the kinetochores
Reactome Imported
    Subnetwork: Autodegradation of the E3 ubiquitin ligase COP1
Reactome Imported
    Subnetwork: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Reactome Imported
    Subnetwork: G1/S DNA Damage Checkpoints
Reactome Imported
    Subnetwork: G2/M Checkpoints
Reactome Imported
    Subnetwork: G2/M DNA damage checkpoint
Reactome Imported
    Subnetwork: G2/M DNA replication checkpoint
Reactome Imported
    Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex
Reactome Imported
    Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Reactome Imported
    Subnetwork: Mitotic Spindle Checkpoint
Reactome Imported
    Subnetwork: Stabilization of p53
Reactome Imported
    Subnetwork: Transcriptional activation of cell cycle inhibitor p21
Reactome Imported
    Subnetwork: Transcriptional activation of p53 responsive genes
Reactome Imported
    Subnetwork: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Reactome Imported
    Subnetwork: p53-Dependent G1 DNA Damage Response
Reactome Imported
    Subnetwork: p53-Dependent G1/S DNA damage checkpoint
Reactome Imported
    Subnetwork: p53-Independent DNA Damage Response
Reactome Imported
    Subnetwork: p53-Independent G1/S DNA damage checkpoint
Reactome Imported
Cell Cycle, Mitotic Reactome Imported
    Subnetwork: APC/C-mediated degradation of cell cycle proteins
Reactome Imported
    Subnetwork: APC/C:Cdc20 mediated degradation of Cyclin B
Reactome Imported
    Subnetwork: APC/C:Cdc20 mediated degradation of Securin
Reactome Imported
    Subnetwork: APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome Imported
    Subnetwork: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Reactome Imported
    Subnetwork: Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome Imported
    Subnetwork: Activation of the pre-replicative complex
Reactome Imported
    Subnetwork: Assembly of the ORC complex at the origin of replication
Reactome Imported
    Subnetwork: Assembly of the pre-replicative complex
Reactome Imported
    Subnetwork: Association of licensing factors with the pre-replicative complex
Reactome Imported
    Subnetwork: Autodegradation of Cdh1 by Cdh1:APC/C
Reactome Imported
    Subnetwork: CDC6 association with the ORC:origin complex
Reactome Imported
    Subnetwork: CDK-mediated phosphorylation and removal of Cdc6
Reactome Imported
    Subnetwork: CDT1 association with the CDC6:ORC:origin complex
Reactome Imported
    Subnetwork: Centrosome maturation
Reactome Imported
    Subnetwork: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Reactome Imported
    Subnetwork: Cyclin A/B1 associated events during G2/M transition
Reactome Imported
    Subnetwork: Cyclin A:Cdk2-associated events at S phase entry
Reactome Imported
    Subnetwork: Cyclin B2 mediated events
Reactome Imported
    Subnetwork: Cyclin D associated events in G1
Reactome Imported
    Subnetwork: Cyclin E associated events during G1/S transition
Reactome Imported
    Subnetwork: DNA Replication Pre-Initiation
Reactome Imported
    Subnetwork: DNA replication initiation
Reactome Imported
    Subnetwork: DNA strand elongation
Reactome Imported
    Subnetwork: E2F mediated regulation of DNA replication
Reactome Imported
    Subnetwork: E2F-enabled inhibition of pre-replication complex formation
Reactome Imported
    Subnetwork: G1 Phase
Reactome Imported
    Subnetwork: G1/S Transition
Reactome Imported
    Subnetwork: G1/S-Specific Transcription
Reactome Imported
    Subnetwork: G2 Phase
Reactome Imported
    Subnetwork: G2/M Transition
Reactome Imported
    Subnetwork: Golgi Cisternae Pericentriolar Stack Reorganization
Reactome Imported
    Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex
Reactome Imported
    Subnetwork: Inhibition of replication initiation of damaged DNA by Rb/E2F1
Reactome Imported
    Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Reactome Imported
    Subnetwork: Lagging Strand Synthesis
Reactome Imported
    Subnetwork: Leading Strand Synthesis
Reactome Imported
    Subnetwork: Loss of Nlp from mitotic centrosomes
Reactome Imported
    Subnetwork: Loss of proteins required for interphase microtubule organization from the centrosome
Reactome Imported
    Subnetwork: M Phase
Reactome Imported
    Subnetwork: M/G1 Transition
Reactome Imported
    Subnetwork: Mitotic G1-G1/S phases
Reactome Imported
    Subnetwork: Mitotic G2-G2/M phases
Reactome Imported
    Subnetwork: Mitotic M-M/G1 phases
Reactome Imported
    Subnetwork: Mitotic Metaphase/Anaphase Transition
Reactome Imported
    Subnetwork: Mitotic Prometaphase
Reactome Imported
    Subnetwork: Mitotic Prophase
Reactome Imported
    Subnetwork: Mitotic Telophase /Cytokinesis
Reactome Imported
    Subnetwork: Orc1 removal from chromatin
Reactome Imported
    Subnetwork: Phosphorylation of Emi1
Reactome Imported
    Subnetwork: Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome Imported
    Subnetwork: Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
Reactome Imported
    Subnetwork: Phosphorylation of the APC/C
Reactome Imported
    Subnetwork: Polo-like kinase mediated events
Reactome Imported
    Subnetwork: Polymerase switching
Reactome Imported
    Subnetwork: Processive synthesis on the lagging strand
Reactome Imported
    Subnetwork: Recruitment of NuMA to mitotic centrosomes
Reactome Imported
    Subnetwork: Recruitment of mitotic centrosome proteins and complexes
Reactome Imported
    Subnetwork: Regulation of APC/C activators between G1/S and early anaphase
Reactome Imported
    Subnetwork: Regulation of DNA replication
Reactome Imported
    Subnetwork: Regulation of mitotic cell cycle
Reactome Imported
    Subnetwork: Removal of licensing factors from origins
Reactome Imported
    Subnetwork: Removal of the Flap Intermediate
Reactome Imported
    Subnetwork: S Phase
Reactome Imported
    Subnetwork: SCF(Skp2)-mediated degradation of p27/p21
Reactome Imported
    Subnetwork: SCF-beta-TrCP mediated degradation of Emi1
Reactome Imported
    Subnetwork: Switching of origins to a post-replicative state
Reactome Imported
    Subnetwork: Synthesis of DNA
Reactome Imported
    Subnetwork: Ubiquitin-dependent degradation of Cyclin D
Reactome Imported
    Subnetwork: Ubiquitin-dependent degradation of Cyclin D1
Reactome Imported
    Subnetwork: Unwinding of DNA
Reactome Imported
Cell junction organization Reactome Imported
    Subnetwork: Adherens junctions interactions
Reactome Imported
    Subnetwork: Cell-cell junction organization
Reactome Imported
    Subnetwork: Cell-extracellular matrix interactions
Reactome Imported
    Subnetwork: Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Reactome Imported
    Subnetwork: Nectin/Necl trans heterodimerization
Reactome Imported
    Subnetwork: Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Reactome Imported
    Subnetwork: Tight junction interactions
Reactome Imported
    Subnetwork: Type I hemidesmosome assembly
Reactome Imported
Chromosome Maintenance Reactome Imported
    Subnetwork: Deposition of New CENPA-containing Nucleosomes at the Centromere
Reactome Imported
    Subnetwork: Extension of Telomeres
Reactome Imported
    Subnetwork: Nucleosome assembly
Reactome Imported
    Subnetwork: Packaging Of Telomere Ends
Reactome Imported
    Subnetwork: Polymerase switching on the C-strand of the telomere
Reactome Imported
    Subnetwork: Processive synthesis on the C-strand of the telomere
Reactome Imported
    Subnetwork: Removal of the Flap Intermediate from the C-strand
Reactome Imported
    Subnetwork: Telomere C-strand (Lagging Strand) Synthesis
Reactome Imported
    Subnetwork: Telomere C-strand synthesis initiation
Reactome Imported
    Subnetwork: Telomere Extension By Telomerase
Reactome Imported
    Subnetwork: Telomere Maintenance
Reactome Imported
DNA Repair Reactome Imported
    Subnetwork: ABH2 mediated Reversal of Alkylation Damage
Reactome Imported
    Subnetwork: ABH3 mediated Reversal of Alkylation Damage
Reactome Imported
    Subnetwork: ATM mediated phosphorylation of repair proteins
Reactome Imported
    Subnetwork: ATM mediated response to DNA double-strand break
Reactome Imported
    Subnetwork: Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks
Reactome Imported
    Subnetwork: Assembly of the RAD51-ssDNA nucleoprotein complex
Reactome Imported
    Subnetwork: Base Excision Repair
Reactome Imported
    Subnetwork: Base-Excision Repair, AP Site Formation
Reactome Imported
    Subnetwork: Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
Reactome Imported
    Subnetwork: Cleavage of the damaged purine
Reactome Imported
    Subnetwork: Cleavage of the damaged pyrimidine
Reactome Imported
    Subnetwork: DNA Damage Bypass
Reactome Imported
    Subnetwork: DNA Damage Recognition in GG-NER
Reactome Imported
    Subnetwork: DNA Damage Reversal
Reactome Imported
    Subnetwork: Depurination
Reactome Imported
    Subnetwork: Depyrimidination
Reactome Imported
    Subnetwork: Displacement of DNA glycosylase by APE1
Reactome Imported
    Subnetwork: Double-Strand Break Repair
Reactome Imported
    Subnetwork: Dual incision reaction in GG-NER
Reactome Imported
    Subnetwork: Dual incision reaction in TC-NER
Reactome Imported
    Subnetwork: Fanconi Anemia pathway
Reactome Imported
    Subnetwork: Formation of incision complex in GG-NER
Reactome Imported
    Subnetwork: Formation of transcription-coupled NER (TC-NER) repair complex
Reactome Imported
    Subnetwork: Gap-filling DNA repair synthesis and ligation in GG-NER
Reactome Imported
    Subnetwork: Gap-filling DNA repair synthesis and ligation in TC-NER
Reactome Imported
    Subnetwork: Global Genomic NER (GG-NER)
Reactome Imported
    Subnetwork: Homologous DNA pairing and strand exchange
Reactome Imported
    Subnetwork: Homologous Recombination Repair
Reactome Imported
    Subnetwork: Homologous recombination repair of replication-independent double-strand breaks
Reactome Imported
    Subnetwork: MRN complex relocalizes to nuclear foci
Reactome Imported
    Subnetwork: Nonhomologous End-joining (NHEJ)
Reactome Imported
    Subnetwork: Nucleotide Excision Repair
Reactome Imported
    Subnetwork: Presynaptic phase of homologous DNA pairing and strand exchange
Reactome Imported
    Subnetwork: Processing of DNA double-strand break ends
Reactome Imported
    Subnetwork: Processing of DNA ends prior to end rejoining
Reactome Imported
    Subnetwork: Recognition and association of DNA glycosylase with site containing an affected purine
Reactome Imported
    Subnetwork: Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Reactome Imported
    Subnetwork: Recruitment of repair and signaling proteins to double-strand breaks
Reactome Imported
    Subnetwork: Regulation of the Fanconi anemia pathway
Reactome Imported
    Subnetwork: Removal of DNA patch containing abasic residue
Reactome Imported
    Subnetwork: Repair synthesis for gap-filling by DNA polymerase in TC-NER
Reactome Imported
    Subnetwork: Repair synthesis of patch ~27-30 bases long by DNA polymerase
Reactome Imported
    Subnetwork: Resolution of AP sites via the multiple-nucleotide patch replacement pathway
Reactome Imported
    Subnetwork: Resolution of AP sites via the single-nucleotide replacement pathway
Reactome Imported
    Subnetwork: Resolution of Abasic Sites (AP sites)
Reactome Imported
    Subnetwork: Resolution of D-loop structures
Reactome Imported
    Subnetwork: Resolution of D-loop structures through Holliday junction intermediates
Reactome Imported
    Subnetwork: Resolution of D-loop structures through synthesis-dependent strand-annealing
Reactome Imported
    Subnetwork: Reversal of Alkylation Damage By DNA Dioxygenases
Reactome Imported
    Subnetwork: Transcription-coupled NER (TC-NER)
Reactome Imported
    Subnetwork: Translesion synthesis by DNA polymerases bypassing lesion on DNA template
Reactome Imported
    Subnetwork: Translesion synthesis by HREV1
Reactome Imported
    Subnetwork: Translesion synthesis by Pol eta
Reactome Imported
    Subnetwork: Translesion synthesis by Pol zeta
Reactome Imported
DNA Replication Reactome Imported
    Subnetwork: Activation of the pre-replicative complex
Reactome Imported
    Subnetwork: Assembly of the ORC complex at the origin of replication
Reactome Imported
    Subnetwork: Assembly of the pre-replicative complex
Reactome Imported
    Subnetwork: Association of licensing factors with the pre-replicative complex
Reactome Imported
    Subnetwork: CDC6 association with the ORC:origin complex
Reactome Imported
    Subnetwork: CDK-mediated phosphorylation and removal of Cdc6
Reactome Imported
    Subnetwork: CDT1 association with the CDC6:ORC:origin complex
Reactome Imported
    Subnetwork: DNA Replication Pre-Initiation
Reactome Imported
    Subnetwork: DNA replication initiation
Reactome Imported
    Subnetwork: DNA strand elongation
Reactome Imported
    Subnetwork: Golgi Cisternae Pericentriolar Stack Reorganization
Reactome Imported
    Subnetwork: Lagging Strand Synthesis
Reactome Imported
    Subnetwork: Leading Strand Synthesis
Reactome Imported
    Subnetwork: M Phase
Reactome Imported
    Subnetwork: M/G1 Transition
Reactome Imported
    Subnetwork: Mitotic M-M/G1 phases
Reactome Imported
    Subnetwork: Mitotic Metaphase/Anaphase Transition
Reactome Imported
    Subnetwork: Mitotic Prometaphase
Reactome Imported
    Subnetwork: Mitotic Prophase
Reactome Imported
    Subnetwork: Mitotic Telophase /Cytokinesis
Reactome Imported
    Subnetwork: Orc1 removal from chromatin
Reactome Imported
    Subnetwork: Polymerase switching
Reactome Imported
    Subnetwork: Processive synthesis on the lagging strand
Reactome Imported
    Subnetwork: Regulation of DNA replication
Reactome Imported
    Subnetwork: Removal of licensing factors from origins
Reactome Imported
    Subnetwork: Removal of the Flap Intermediate
Reactome Imported
    Subnetwork: Switching of origins to a post-replicative state
Reactome Imported
    Subnetwork: Synthesis of DNA
Reactome Imported
    Subnetwork: Unwinding of DNA
Reactome Imported
Diabetes pathways Reactome Imported
    Subnetwork: Activation of Chaperones by ATF6-alpha
Reactome Imported
    Subnetwork: Activation of Chaperones by IRE1alpha
Reactome Imported
    Subnetwork: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
Reactome Imported
    Subnetwork: Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
Reactome Imported
    Subnetwork: Insulin Synthesis and Processing
Reactome Imported
    Subnetwork: PERK regulated gene expression
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Acetylcholine
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Fatty Acids Bound to GPR40 (FFAR1)
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Free Fatty Acids
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Glucagon-like Peptide-1
Reactome Imported
    Subnetwork: Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Reactome Imported
    Subnetwork: Synthesis, Secretion, and Deacylation of Ghrelin
Reactome Imported
    Subnetwork: Unfolded Protein Response
Reactome Imported
Elevation of cytosolic Ca2+ levels Reactome Imported
Elongation arrest and recovery Reactome Imported
Gene Expression Reactome Imported
    Subnetwork: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Reactome Imported
    Subnetwork: Cap-dependent Translation Initiation
Reactome Imported
    Subnetwork: Cleavage of Growing Transcript in the Termination Region
Reactome Imported
    Subnetwork: Cytosolic tRNA aminoacylation
Reactome Imported
    Subnetwork: Eukaryotic Translation Elongation
Reactome Imported
    Subnetwork: Eukaryotic Translation Initiation
Reactome Imported
    Subnetwork: Eukaryotic Translation Termination
Reactome Imported
    Subnetwork: Formation and Maturation of mRNA Transcript
Reactome Imported
    Subnetwork: Formation of RNA Pol II elongation complex
Reactome Imported
    Subnetwork: Formation of a pool of free 40S subunits
Reactome Imported
    Subnetwork: Formation of the Early Elongation Complex
Reactome Imported
    Subnetwork: Formation of the ternary complex, and subsequently, the 43S complex
Reactome Imported
    Subnetwork: GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome Imported
    Subnetwork: Generic Transcription Pathway
Reactome Imported
    Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression
Reactome Imported
    Subnetwork: Mitochondrial tRNA aminoacylation
Reactome Imported
    Subnetwork: Notch-HLH transcription pathway
Reactome Imported
    Subnetwork: Nuclear Receptor transcription pathway
Reactome Imported
    Subnetwork: Peptide chain elongation
Reactome Imported
    Subnetwork: Processing of Capped Intron-Containing Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Capped Intronless Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Capped Transcripts
Reactome Imported
    Subnetwork: Processing of Intronless Pre-mRNAs
Reactome Imported
    Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE
Reactome Imported
    Subnetwork: RNA Polymerase II Pre-transcription Events
Reactome Imported
    Subnetwork: RNA Polymerase II Promoter Escape
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Elongation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Termination
Reactome Imported
    Subnetwork: Recycling of eIF2:GDP
Reactome Imported
    Subnetwork: Ribosomal scanning and start codon recognition
Reactome Imported
    Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP independent Processing of Histone Pre-mRNAs
Reactome Imported
    Subnetwork: Translation
Reactome Imported
    Subnetwork: Translation initiation complex formation
Reactome Imported
    Subnetwork: Transport of Mature Transcript to Cytoplasm
Reactome Imported
    Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts
Reactome Imported
    Subnetwork: Transport of the SLBP Dependant Mature mRNA
Reactome Imported
    Subnetwork: Transport of the SLBP independent Mature mRNA
Reactome Imported
    Subnetwork: mRNA 3'-end processing
Reactome Imported
    Subnetwork: mRNA Capping
Reactome Imported
    Subnetwork: mRNA Splicing
Reactome Imported
    Subnetwork: mRNA Splicing - Major Pathway
Reactome Imported
    Subnetwork: mRNA Splicing - Minor Pathway
Reactome Imported
    Subnetwork: tRNA Aminoacylation
Reactome Imported
HIV Infection Reactome Imported
    Subnetwork: 2-LTR circle formation
Reactome Imported
    Subnetwork: APOBEC3G mediated resistance to HIV-1 infection
Reactome Imported
    Subnetwork: Abortive elongation of HIV-1 transcript in the absence of Tat
Reactome Imported
    Subnetwork: Autointegration results in viral DNA circles
Reactome Imported
    Subnetwork: Binding and entry of HIV virion
Reactome Imported
    Subnetwork: Early Phase of HIV Life Cycle
Reactome Imported
    Subnetwork: Formation of HIV-1 elongation complex containing HIV-1 Tat
Reactome Imported
    Subnetwork: Formation of HIV-1 elongation complex in the absence of HIV-1 Tat
Reactome Imported
    Subnetwork: Formation of the HIV-1 Early Elongation Complex
Reactome Imported
    Subnetwork: HIV Life Cycle
Reactome Imported
    Subnetwork: HIV-1 Transcription Elongation
Reactome Imported
    Subnetwork: HIV-1 Transcription Initiation
Reactome Imported
    Subnetwork: HIV-1 elongation arrest and recovery
Reactome Imported
    Subnetwork: Host Interactions of HIV factors
Reactome Imported
    Subnetwork: Integration of provirus
Reactome Imported
    Subnetwork: Integration of viral DNA into host genomic DNA
Reactome Imported
    Subnetwork: Interactions of Rev with host cellular proteins
Reactome Imported
    Subnetwork: Interactions of Tat with host cellular proteins
Reactome Imported
    Subnetwork: Interactions of Vpr with host cellular proteins
Reactome Imported
    Subnetwork: Late Phase of HIV Life Cycle
Reactome Imported
    Subnetwork: Minus-strand DNA synthesis
Reactome Imported
    Subnetwork: Nef Mediated CD4 Down-regulation
Reactome Imported
    Subnetwork: Nef Mediated CD8 Down-regulation
Reactome Imported
    Subnetwork: Nef and signal transduction
Reactome Imported
    Subnetwork: Nef mediated downregulation of CD28 cell surface expression
Reactome Imported
    Subnetwork: Nef mediated downregulation of MHC class I complex cell surface expression
Reactome Imported
    Subnetwork: Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
Reactome Imported
    Subnetwork: Nuclear import of Rev protein
Reactome Imported
    Subnetwork: Pausing and recovery of HIV-1 elongation
Reactome Imported
    Subnetwork: Pausing and recovery of Tat-mediated HIV-1 elongation
Reactome Imported
    Subnetwork: Plus-strand DNA synthesis
Reactome Imported
    Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE
Reactome Imported
    Subnetwork: RNA Polymerase II HIV-1 Promoter Escape
Reactome Imported
    Subnetwork: Rev-mediated nuclear export of HIV-1 RNA
Reactome Imported
    Subnetwork: Reverse Transcription of HIV RNA
Reactome Imported
    Subnetwork: Tat-mediated HIV-1 elongation arrest and recovery
Reactome Imported
    Subnetwork: Tat-mediated elongation of the HIV-1 transcript
Reactome Imported
    Subnetwork: The role of Nef in HIV-1 replication and disease pathogenesis
Reactome Imported
    Subnetwork: Transcription of the HIV genome
Reactome Imported
    Subnetwork: Uncoating of the HIV Virion
Reactome Imported
    Subnetwork: Vif-mediated degradation of APOBEC3G
Reactome Imported
    Subnetwork: Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
Reactome Imported
    Subnetwork: Vpr-mediated nuclear import of PICs
Reactome Imported
    Subnetwork: Vpu mediated degradation of CD4
Reactome Imported
Hemostasis Reactome Imported
    Subnetwork: ADP signalling through P2Y purinoceptor 1
Reactome Imported
    Subnetwork: ADP signalling through P2Y purinoceptor 12
Reactome Imported
    Subnetwork: Adrenaline signalling through Alpha-2 adrenergic receptor
Reactome Imported
    Subnetwork: Arachidonate production from DAG
Reactome Imported
    Subnetwork: Basigin interactions
Reactome Imported
    Subnetwork: Cell surface interactions at the vascular wall
Reactome Imported
    Subnetwork: Collagen adhesion via GPVI
Reactome Imported
    Subnetwork: Collagen adhesion via Gp IV
Reactome Imported
    Subnetwork: Collagen adhesion via alpha 2 beta 1 glycoprotein
Reactome Imported
    Subnetwork: Common Pathway
Reactome Imported
    Subnetwork: Disinhibition of SNARE formation
Reactome Imported
    Subnetwork: Dissolution of Fibrin Clot
Reactome Imported
    Subnetwork: Effects of PIP2 hydrolysis
Reactome Imported
    Subnetwork: Extrinsic Pathway
Reactome Imported
    Subnetwork: Formation of Fibrin Clot (Clotting Cascade)
Reactome Imported
    Subnetwork: Formation of Platelet plug
Reactome Imported
    Subnetwork: GPVI-mediated activation cascade
Reactome Imported
    Subnetwork: Grb2:SOS provides linkage to MAPK signaling for Intergrins
Reactome Imported
    Subnetwork: Integrin alphaIIbbeta3 signaling
Reactome Imported
    Subnetwork: Intrinsic Pathway
Reactome Imported
    Subnetwork: PECAM1 interactions
Reactome Imported
    Subnetwork: Platelet Activation
Reactome Imported
    Subnetwork: Platelet Adhesion to exposed collagen
Reactome Imported
    Subnetwork: Platelet Aggregation (Plug Formation)
Reactome Imported
    Subnetwork: Platelet activation triggers
Reactome Imported
    Subnetwork: Platelet degranulation
Reactome Imported
    Subnetwork: Response to elevated platelet cytosolic Ca2+
Reactome Imported
    Subnetwork: Signal amplification
Reactome Imported
    Subnetwork: Thrombin signalling through proteinase activated receptors (PARs)
Reactome Imported
    Subnetwork: Thromboxane signalling through TP receptor
Reactome Imported
    Subnetwork: Tie2 Signaling
Reactome Imported
    Subnetwork: p130Cas linkage to MAPK signaling for integrins
Reactome Imported
    Subnetwork: vWF interaction with collagen
Reactome Imported
Hormone biosynthesis Reactome Imported
    Subnetwork: Amine-derived hormones
Reactome Imported
    Subnetwork: Androgen biosynthesis
Reactome Imported
    Subnetwork: Catecholamine biosynthesis
Reactome Imported
    Subnetwork: Estrogen biosynthesis
Reactome Imported
    Subnetwork: Glucocorticoid biosynthesis
Reactome Imported
    Subnetwork: Glycoprotein hormones
Reactome Imported
    Subnetwork: Leukotriene synthesis
Reactome Imported
    Subnetwork: Mineralocorticoid biosynthesis
Reactome Imported
    Subnetwork: Peptide hormone biosynthesis
Reactome Imported
    Subnetwork: Pregnenolone biosynthesis
Reactome Imported
    Subnetwork: Prostanoid metabolism
Reactome Imported
    Subnetwork: Regulation of thyroid hormone activity
Reactome Imported
    Subnetwork: Serotonin and melatonin biosynthesis
Reactome Imported
    Subnetwork: Steroid hormones
Reactome Imported
    Subnetwork: Thyroxine biosynthesis
Reactome Imported
    Subnetwork: Vitamin D (calciferol) metabolism
Reactome Imported
Influenza Infection Reactome Imported
    Subnetwork: Assembly of Viral Components at the Budding Site
Reactome Imported
    Subnetwork: Budding
Reactome Imported
    Subnetwork: Entry of Influenza Virion into Host Cell via Endocytosis
Reactome Imported
    Subnetwork: Export of Viral Ribonucleoproteins from Nucleus
Reactome Imported
    Subnetwork: Fusion and Uncoating of the Influenza Virion
Reactome Imported
    Subnetwork: Fusion of the Influenza Virion to the Host Cell Endosome
Reactome Imported
    Subnetwork: Host Interactions with Influenza Factors
Reactome Imported
    Subnetwork: Influenza Life Cycle
Reactome Imported
    Subnetwork: Influenza Viral RNA Transcription and Replication
Reactome Imported
    Subnetwork: Influenza Virus Induced Apoptosis
Reactome Imported
    Subnetwork: Inhibition of Host mRNA Processing and RNA Silencing
Reactome Imported
    Subnetwork: Inhibition of IFN-beta
Reactome Imported
    Subnetwork: Inhibition of Interferon Synthesis
Reactome Imported
    Subnetwork: Inhibition of PKR
Reactome Imported
    Subnetwork: NEP/NS2 Interacts with the Cellular Export Machinery
Reactome Imported
    Subnetwork: NS1 Mediated Effects on Host Pathways
Reactome Imported
    Subnetwork: Packaging of Eight RNA Segments
Reactome Imported
    Subnetwork: Release
Reactome Imported
    Subnetwork: Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus
Reactome Imported
    Subnetwork: Transport of Ribonucleoproteins into the Host Nucleus
Reactome Imported
    Subnetwork: Uncoating of the Influenza Virion
Reactome Imported
    Subnetwork: Viral Messenger RNA Synthesis
Reactome Imported
    Subnetwork: Viral RNP Complexes in the Host Cell Nucleus
Reactome Imported
    Subnetwork: Viral mRNA Translation
Reactome Imported
    Subnetwork: Virus Assembly and Release
Reactome Imported
    Subnetwork: cRNA Synthesis
Reactome Imported
    Subnetwork: vRNA Synthesis
Reactome Imported
    Subnetwork: vRNP Assembly
Reactome Imported
Inhibition of HSL Reactome Imported
Integration of energy metabolism Reactome Imported
    Subnetwork: AMPK inhibits chREBP transcriptional activation activity
Reactome Imported
    Subnetwork: ChREBP activates metabolic gene expression
Reactome Imported
    Subnetwork: Glucagon signaling in metabolic regulation
Reactome Imported
    Subnetwork: Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
Reactome Imported
    Subnetwork: Insulin effects increased synthesis of Xylulose-5-Phosphate
Reactome Imported
    Subnetwork: PKA activation in glucagon signalling
Reactome Imported
    Subnetwork: PKA-mediated phosphorylation of key metabolic factors
Reactome Imported
    Subnetwork: PP2A-mediated dephosphorylation of key metabolic factors
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Acetylcholine
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Fatty Acids Bound to GPR40 (FFAR1)
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Free Fatty Acids
Reactome Imported
    Subnetwork: Regulation of Insulin Secretion by Glucagon-like Peptide-1
Reactome Imported
Integrin cell surface interactions Reactome Imported
    Subnetwork: Grb2:SOS provides linkage to MAPK signaling for Intergrins
Reactome Imported
    Subnetwork: Integrin alphaIIbbeta3 signaling
Reactome Imported
    Subnetwork: p130Cas linkage to MAPK signaling for integrins
Reactome Imported
Membrane Trafficking Reactome Imported
    Subnetwork: COPI Mediated Transport
Reactome Imported
    Subnetwork: COPII (Coat Protein 2) Mediated Vesicle Transport
Reactome Imported
    Subnetwork: Clathrin derived vesicle budding
Reactome Imported
    Subnetwork: ER to Golgi Transport
Reactome Imported
    Subnetwork: Formation of annular gap junctions
Reactome Imported
    Subnetwork: Gap junction assembly
Reactome Imported
    Subnetwork: Gap junction degradation
Reactome Imported
    Subnetwork: Gap junction trafficking
Reactome Imported
    Subnetwork: Gap junction trafficking and regulation
Reactome Imported
    Subnetwork: Golgi Associated Vesicle Biogenesis
Reactome Imported
    Subnetwork: Golgi to ER Retrograde Transport
Reactome Imported
    Subnetwork: Lysosome Vesicle Biogenesis
Reactome Imported
    Subnetwork: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Reactome Imported
    Subnetwork: Oligomerization of connexins into connexons
Reactome Imported
    Subnetwork: Regulation of gap junction activity
Reactome Imported
    Subnetwork: Transport of connexins along the secretory pathway
Reactome Imported
    Subnetwork: Transport of connexons to the plasma membrane
Reactome Imported
    Subnetwork: c-src mediated regulation of Cx43 function and closure of gap junctions
Reactome Imported
    Subnetwork: trans-Golgi Network Vesicle Budding
Reactome Imported
Metabolism of RNA Reactome Imported
    Subnetwork: Deadenylation of mRNA
Reactome Imported
    Subnetwork: Deadenylation-dependent mRNA decay
Reactome Imported
    Subnetwork: Metabolism of mRNA
Reactome Imported
    Subnetwork: Metabolism of non-coding RNA
Reactome Imported
    Subnetwork: mRNA Decay by 3' to 5' Exoribonuclease
Reactome Imported
    Subnetwork: mRNA Decay by 5' to 3' Exoribonuclease
Reactome Imported
    Subnetwork: snRNP Assembly
Reactome Imported
Metabolism of amino acids and derivatives Reactome Imported
    Subnetwork: Agmatine biosynthesis
Reactome Imported
    Subnetwork: Amine-derived hormones
Reactome Imported
    Subnetwork: Amino acid synthesis and interconversion (transamination)
Reactome Imported
    Subnetwork: Amino acid transport across the plasma membrane
Reactome Imported
    Subnetwork: Branched-chain amino acid catabolism
Reactome Imported
    Subnetwork: Carnitine synthesis
Reactome Imported
    Subnetwork: Catecholamine biosynthesis
Reactome Imported
    Subnetwork: Creatine metabolism
Reactome Imported
    Subnetwork: Glycoprotein hormones
Reactome Imported
    Subnetwork: Glyoxylate metabolism
Reactome Imported
    Subnetwork: Histidine catabolism
Reactome Imported
    Subnetwork: Interconversion of polyamines
Reactome Imported
    Subnetwork: Lysine catabolism
Reactome Imported
    Subnetwork: Metabolism of polyamines
Reactome Imported
    Subnetwork: Peptide hormone biosynthesis
Reactome Imported
    Subnetwork: Phenylalanine and tyrosine catabolism
Reactome Imported
    Subnetwork: Proline catabolism
Reactome Imported
    Subnetwork: Regulation of ornithine decarboxylase (ODC)
Reactome Imported
    Subnetwork: Regulation of thyroid hormone activity
Reactome Imported
    Subnetwork: Serotonin and melatonin biosynthesis
Reactome Imported
    Subnetwork: Thyroxine biosynthesis
Reactome Imported
    Subnetwork: Tryptophan catabolism
Reactome Imported
    Subnetwork: Urea cycle
Reactome Imported
Metabolism of carbohydrates Reactome Imported
    Subnetwork: 5-Phosphoribose 1-diphosphate biosynthesis
Reactome Imported
    Subnetwork: Digestion of dietary carbohydrate
Reactome Imported
    Subnetwork: Fructose catabolism
Reactome Imported
    Subnetwork: Galactose catabolism
Reactome Imported
    Subnetwork: Gluconeogenesis
Reactome Imported
    Subnetwork: Glucose metabolism
Reactome Imported
    Subnetwork: Glucose transport
Reactome Imported
    Subnetwork: Glycogen breakdown (glycogenolysis)
Reactome Imported
    Subnetwork: Glycogen synthesis
Reactome Imported
    Subnetwork: Glycolysis
Reactome Imported
    Subnetwork: Hexose transport
Reactome Imported
    Subnetwork: Pentose phosphate pathway (hexose monophosphate shunt)
Reactome Imported
    Subnetwork: Regulation of Glucokinase by Glucokinase Regulatory Protein
Reactome Imported
Metabolism of lipids and lipoproteins Reactome Imported
    Subnetwork: Alpha-oxidation of phytanate
Reactome Imported
    Subnetwork: Androgen biosynthesis
Reactome Imported
    Subnetwork: Beta oxidation of butanoyl-CoA to acetyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
Reactome Imported
    Subnetwork: Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
Reactome Imported
    Subnetwork: Beta oxidation of myristoyl-CoA to lauroyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Reactome Imported
    Subnetwork: Beta-oxidation of pristanoyl-CoA
Reactome Imported
    Subnetwork: Beta-oxidation of very long chain fatty acids
Reactome Imported
    Subnetwork: Bile acid and bile salt metabolism
Reactome Imported
    Subnetwork: Cholesterol biosynthesis
Reactome Imported
    Subnetwork: Chylomicron-mediated lipid transport
Reactome Imported
    Subnetwork: Digestion of dietary lipid
Reactome Imported
    Subnetwork: Estrogen biosynthesis
Reactome Imported
    Subnetwork: Fatty Acyl-CoA Biosynthesis
Reactome Imported
    Subnetwork: Fatty acid, triacylglycerol, and ketone body metabolism
Reactome Imported
    Subnetwork: Formation of Acetoacetic Acid
Reactome Imported
    Subnetwork: Glucocorticoid biosynthesis
Reactome Imported
    Subnetwork: HDL-mediated lipid transport
Reactome Imported
    Subnetwork: Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
Reactome Imported
    Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix
Reactome Imported
    Subnetwork: Ketone body metabolism
Reactome Imported
    Subnetwork: LDL-mediated lipid transport
Reactome Imported
    Subnetwork: Leukotriene synthesis
Reactome Imported
    Subnetwork: Lipid digestion, mobilization, and transport
Reactome Imported
    Subnetwork: Lipoprotein metabolism
Reactome Imported
    Subnetwork: Metabolism of steroid hormones and vitamin D
Reactome Imported
    Subnetwork: Mineralocorticoid biosynthesis
Reactome Imported
    Subnetwork: Mitochondrial Fatty Acid Beta-Oxidation
Reactome Imported
    Subnetwork: NADPH regeneration
Reactome Imported
    Subnetwork: Peroxisomal lipid metabolism
Reactome Imported
    Subnetwork: Plasmalogen biosynthesis
Reactome Imported
    Subnetwork: Pregnenolone biosynthesis
Reactome Imported
    Subnetwork: Propionyl-CoA catabolism
Reactome Imported
    Subnetwork: Prostanoid metabolism
Reactome Imported
    Subnetwork: Recycling of bile acids and salts
Reactome Imported
    Subnetwork: Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Reactome Imported
    Subnetwork: Sphingolipid metabolism
Reactome Imported
    Subnetwork: Synthesis of Ketone Bodies
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Reactome Imported
    Subnetwork: Synthesis of very long-chain fatty acyl-CoAs
Reactome Imported
    Subnetwork: Trafficking of dietary sterols
Reactome Imported
    Subnetwork: Triglyceride Biosynthesis
Reactome Imported
    Subnetwork: Utilization of Ketone Bodies
Reactome Imported
    Subnetwork: Vitamin D (calciferol) metabolism
Reactome Imported
    Subnetwork: mitochondrial fatty acid beta-oxidation of saturated fatty acids
Reactome Imported
    Subnetwork: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome Imported
Metabolism of nitric oxide Reactome Imported
    Subnetwork: NOSIP mediated eNOS trafficking
Reactome Imported
    Subnetwork: NOSTRIN mediated eNOS trafficking
Reactome Imported
    Subnetwork: eNOS activation
Reactome Imported
    Subnetwork: eNOS activation and regulation
Reactome Imported
Metabolism of nucleotides Reactome Imported
    Subnetwork: Purine catabolism
Reactome Imported
    Subnetwork: Purine metabolism
Reactome Imported
    Subnetwork: Purine ribonucleoside monophosphate biosynthesis
Reactome Imported
    Subnetwork: Purine salvage
Reactome Imported
    Subnetwork: Pyrimidine biosynthesis
Reactome Imported
    Subnetwork: Pyrimidine catabolism
Reactome Imported
    Subnetwork: Pyrimidine metabolism
Reactome Imported
    Subnetwork: Pyrimidine salvage reactions
Reactome Imported
    Subnetwork: Synthesis and interconversion of nucleotide di- and triphosphates
Reactome Imported
    Subnetwork: Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Reactome Imported
Metabolism of porphyrins Reactome Imported
    Subnetwork: Heme biosynthesis
Reactome Imported
    Subnetwork: Heme degradation
Reactome Imported
Metabolism of proteins Reactome Imported
    Subnetwork: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Reactome Imported
    Subnetwork: Association of TriC/CCT with target proteins during biosynthesis
Reactome Imported
    Subnetwork: Attachment of GPI anchor to uPAR
Reactome Imported
    Subnetwork: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome Imported
    Subnetwork: Cap-dependent Translation Initiation
Reactome Imported
    Subnetwork: Chaperonin-mediated protein folding
Reactome Imported
    Subnetwork: Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Reactome Imported
    Subnetwork: Eukaryotic Translation Elongation
Reactome Imported
    Subnetwork: Eukaryotic Translation Initiation
Reactome Imported
    Subnetwork: Eukaryotic Translation Termination
Reactome Imported
    Subnetwork: Folding of actin by CCT/TriC
Reactome Imported
    Subnetwork: Formation of a pool of free 40S subunits
Reactome Imported
    Subnetwork: Formation of the ternary complex, and subsequently, the 43S complex
Reactome Imported
    Subnetwork: Formation of tubulin folding intermediates by CCT/TriC
Reactome Imported
    Subnetwork: GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome Imported
    Subnetwork: Gamma-carboxylation of protein precursors
Reactome Imported
    Subnetwork: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Reactome Imported
    Subnetwork: Hypusine synthesis from eIF5A-lysine
Reactome Imported
    Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression
Reactome Imported
    Subnetwork: N-linked glycosylation
Reactome Imported
    Subnetwork: Peptide chain elongation
Reactome Imported
    Subnetwork: Post-chaperonin tubulin folding pathway
Reactome Imported
    Subnetwork: Post-translational modification: gamma carboxylation and hypusine formation
Reactome Imported
    Subnetwork: Post-translational modification: synthesis of GPI-anchored proteins
Reactome Imported
    Subnetwork: Post-translational protein modification
Reactome Imported
    Subnetwork: Prefoldin mediated transfer of substrate to CCT/TriC
Reactome Imported
    Subnetwork: Protein folding
Reactome Imported
    Subnetwork: Recycling of eIF2:GDP
Reactome Imported
    Subnetwork: Removal of aminoterminal propeptides from gamma-carboxylated proteins
Reactome Imported
    Subnetwork: Ribosomal scanning and start codon recognition
Reactome Imported
    Subnetwork: Synthesis of Dolichyl-phosphate
Reactome Imported
    Subnetwork: Synthesis of GDP-mannose
Reactome Imported
    Subnetwork: Synthesis of UDP-N-acetyl-glucosamine
Reactome Imported
    Subnetwork: Synthesis of dolichol-phosphate mannose
Reactome Imported
    Subnetwork: Synthesis of dolichyl-phosphate-glucose
Reactome Imported
    Subnetwork: Synthesis of glycosylphosphatidylinositol (GPI)
Reactome Imported
    Subnetwork: Synthesis of substrates in N-glycan biosythesis
Reactome Imported
    Subnetwork: Translation
Reactome Imported
    Subnetwork: Translation initiation complex formation
Reactome Imported
    Subnetwork: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Reactome Imported
Metabolism of vitamins and cofactors Reactome Imported
    Subnetwork: Biotin metabolism
Reactome Imported
    Subnetwork: Coenzyme A biosynthesis
Reactome Imported
    Subnetwork: Metabolism of folate and pterines
Reactome Imported
    Subnetwork: Metabolism of water-soluble vitamins and cofactors
Reactome Imported
    Subnetwork: Nicotinamide salvaging
Reactome Imported
    Subnetwork: Nicotinate metabolism
Reactome Imported
    Subnetwork: Vitamin B1 (thiamin) metabolism
Reactome Imported
    Subnetwork: Vitamin B2 (riboflavin) metabolism
Reactome Imported
    Subnetwork: Vitamin B5 (pantothenate) metabolism
Reactome Imported
    Subnetwork: Vitamin C (ascorbate) metabolism
Reactome Imported
    Subnetwork: Vitamin D (calciferol) metabolism
Reactome Imported
Muscle contraction Reactome Imported
    Subnetwork: Smooth Muscle Contraction
Reactome Imported
    Subnetwork: Striated Muscle Contraction
Reactome Imported
Myogenesis Reactome Imported
    Subnetwork: CDO in myogenesis
Reactome Imported
Opioid Signalling Reactome Imported
    Subnetwork: Adenylate cyclase activating pathway
Reactome Imported
    Subnetwork: Adenylate cyclase inhibitory pathway
Reactome Imported
    Subnetwork: Ca-dependent events
Reactome Imported
    Subnetwork: CaM pathway
Reactome Imported
    Subnetwork: CaMK IV-mediated phosphorylation of CREB
Reactome Imported
    Subnetwork: Calmodulin induced events
Reactome Imported
    Subnetwork: Cam-PDE 1 activation
Reactome Imported
    Subnetwork: DARPP-32 events
Reactome Imported
    Subnetwork: G-protein activation
Reactome Imported
    Subnetwork: G-protein mediated events
Reactome Imported
    Subnetwork: PKA activation
Reactome Imported
    Subnetwork: PKA-mediated phosphorylation of CREB
Reactome Imported
    Subnetwork: PLC beta mediated events
Reactome Imported
    Subnetwork: phospho-PLA2 pathway
Reactome Imported
PLC-mediated hydrolysis of PIP2 Reactome Imported
Pausing and recovery of elongation Reactome Imported
Post-Elongation Processing of the Transcript Reactome Imported
    Subnetwork: Post-Elongation Processing of Intron-Containing pre-mRNA
Reactome Imported
    Subnetwork: Post-Elongation Processing of Intronless pre-mRNA
Reactome Imported
    Subnetwork: Processing of Capped Intronless Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Intronless Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP independent Processing of Histone Pre-mRNAs
Reactome Imported
    Subnetwork: mRNA 3'-end processing
Reactome Imported
Pyrophosphate hydrolysis Reactome Imported
Pyruvate metabolism and Citric Acid (TCA) cycle Reactome Imported
    Subnetwork: Citric acid cycle (TCA cycle)
Reactome Imported
    Subnetwork: Pyruvate metabolism
Reactome Imported
    Subnetwork: Regulation of pyruvate dehydrogenase (PDH) complex
Reactome Imported
Regulation of activated PAK-2p34 by proteasome mediated degradation Reactome Imported
Regulation of beta-cell development Reactome Imported
    Subnetwork: AKT-mediated inactivation of FOXO1A
Reactome Imported
    Subnetwork: Regulation of gene expression in beta cells
Reactome Imported
    Subnetwork: Regulation of gene expression in early pancreatic precursor cells
Reactome Imported
    Subnetwork: Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Reactome Imported
    Subnetwork: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
Reactome Imported
Regulatory RNA pathways Reactome Imported
    Subnetwork: MicroRNA (miRNA) Biogenesis
Reactome Imported
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Reactome Imported
    Subnetwork: Formation of ATP by chemiosmotic coupling
Reactome Imported
    Subnetwork: Mitochondrial Uncoupling Proteins
Reactome Imported
    Subnetwork: Respiratory electron transport
Reactome Imported
    Subnetwork: The fatty acid cycling model
Reactome Imported
    Subnetwork: The proton buffering model
Reactome Imported
Signaling by BMP Reactome Imported
Signaling by EGFR Reactome Imported
    Subnetwork: EGFR downregulation
Reactome Imported
    Subnetwork: EGFR interacts with phospholipase C-gamma
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: Gab1 signalosome
Reactome Imported
    Subnetwork: Grb2 events in EGFR signaling
Reactome Imported
    Subnetwork: MAP kinase cascade
Reactome Imported
    Subnetwork: MEK activation
Reactome Imported
    Subnetwork: RAF activation
Reactome Imported
    Subnetwork: RAF phosphorylates MEK
Reactome Imported
    Subnetwork: Shc events in EGFR signaling
Reactome Imported
Signaling by FGFR Reactome Imported
    Subnetwork: Downstream signaling of activated FGFR
Reactome Imported
    Subnetwork: FGFR ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1 ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1b ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1c and Klotho ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1c ligand binding and activation
Reactome Imported
    Subnetwork: FGFR2 ligand binding and activation
Reactome Imported
    Subnetwork: FGFR2b ligand binding and activation
Reactome Imported
    Subnetwork: FGFR2c ligand binding and activation
Reactome Imported
    Subnetwork: FGFR3 ligand binding and activation
Reactome Imported
    Subnetwork: FGFR3b ligand binding and activation
Reactome Imported
    Subnetwork: FGFR3c ligand binding and activation
Reactome Imported
    Subnetwork: FGFR4 ligand binding and activation
Reactome Imported
    Subnetwork: FRS2-mediated cascade
Reactome Imported
    Subnetwork: PI-3K cascade
Reactome Imported
    Subnetwork: Phospholipase C-mediated cascade
Reactome Imported
    Subnetwork: SHC-mediated cascade
Reactome Imported
Signaling by GPCR Reactome Imported
    Subnetwork: Adenosine P1 receptors
Reactome Imported
    Subnetwork: Adrenoceptors
Reactome Imported
    Subnetwork: Amine ligand-binding receptors
Reactome Imported
    Subnetwork: Arachidonate production from DAG
Reactome Imported
    Subnetwork: Calcitonin-like ligand receptors
Reactome Imported
    Subnetwork: Chemokine receptors bind chemokines
Reactome Imported
    Subnetwork: Class A/1 (Rhodopsin-like receptors)
Reactome Imported
    Subnetwork: Class B/2 (Secretin family receptors)
Reactome Imported
    Subnetwork: Class C/3 (Metabotropic glutamate/pheromone receptors)
Reactome Imported
    Subnetwork: Dopamine receptors
Reactome Imported
    Subnetwork: Effects of PIP2 hydrolysis
Reactome Imported
    Subnetwork: Eicosanoid ligand-binding receptors
Reactome Imported
    Subnetwork: Formyl peptide receptors bind formyl peptides and many other ligands
Reactome Imported
    Subnetwork: Free fatty acid receptors
Reactome Imported
    Subnetwork: G alpha (12/13) signalling events
Reactome Imported
    Subnetwork: G alpha (i) signalling events
Reactome Imported
    Subnetwork: G alpha (q) signalling events
Reactome Imported
    Subnetwork: G alpha (s) signalling events
Reactome Imported
    Subnetwork: G alpha (z) signalling events
Reactome Imported
    Subnetwork: G beta:gamma signalling through PI3Kgamma
Reactome Imported
    Subnetwork: G beta:gamma signalling through PLC beta
Reactome Imported
    Subnetwork: G-protein beta:gamma signalling
Reactome Imported
    Subnetwork: GPCR downstream signaling
Reactome Imported
    Subnetwork: GPCR ligand binding
Reactome Imported
    Subnetwork: Glucagon-type ligand receptors
Reactome Imported
    Subnetwork: Histamine receptors
Reactome Imported
    Subnetwork: Hormone ligand-binding receptors
Reactome Imported
    Subnetwork: Leukotriene receptors
Reactome Imported
    Subnetwork: Lysosphingolipid and LPA receptors
Reactome Imported
    Subnetwork: Muscarinic acetylcholine receptors
Reactome Imported
    Subnetwork: Nucleotide-like (purinergic) receptors
Reactome Imported
    Subnetwork: Olfactory Signaling Pathway
Reactome Imported
    Subnetwork: Opsins
Reactome Imported
    Subnetwork: Orexin and neuropeptides FF and QRFP bind to their respective receptors
Reactome Imported
    Subnetwork: P2Y receptors
Reactome Imported
    Subnetwork: Peptide ligand-binding receptors
Reactome Imported
    Subnetwork: Prostanoid ligand receptors
Reactome Imported
    Subnetwork: Relaxin receptors
Reactome Imported
    Subnetwork: Serotonin receptors
Reactome Imported
    Subnetwork: Tachykinin receptors bind tachykinins
Reactome Imported
    Subnetwork: Vasopressin-like receptors
Reactome Imported
Signaling by Insulin receptor Reactome Imported
    Subnetwork: Activation of PKB
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: Energy dependent regulation of mTOR by LKB1-AMPK
Reactome Imported
    Subnetwork: IRS activation
Reactome Imported
    Subnetwork: IRS-mediated signalling
Reactome Imported
    Subnetwork: IRS-related events
Reactome Imported
    Subnetwork: Inhibition of TSC complex formation by PKB
Reactome Imported
    Subnetwork: Insulin receptor recycling
Reactome Imported
    Subnetwork: Insulin receptor signalling cascade
Reactome Imported
    Subnetwork: MAP kinase cascade
Reactome Imported
    Subnetwork: MEK activation
Reactome Imported
    Subnetwork: PDE3B signalling
Reactome Imported
    Subnetwork: PI3K Cascade
Reactome Imported
    Subnetwork: PKB-mediated events
Reactome Imported
    Subnetwork: RAF activation
Reactome Imported
    Subnetwork: RAF phosphorylates MEK
Reactome Imported
    Subnetwork: Regulation of AMPK activity via LKB1
Reactome Imported
    Subnetwork: Regulation of Rheb GTPase activity by AMPK
Reactome Imported
    Subnetwork: Release of eIF4E
Reactome Imported
    Subnetwork: S6K1 signalling
Reactome Imported
    Subnetwork: S6K1-mediated signalling
Reactome Imported
    Subnetwork: SHC activation
Reactome Imported
    Subnetwork: SHC-mediated signalling
Reactome Imported
    Subnetwork: SHC-related events
Reactome Imported
    Subnetwork: SOS-mediated signalling
Reactome Imported
    Subnetwork: Signal attenuation
Reactome Imported
    Subnetwork: mTOR signalling
Reactome Imported
    Subnetwork: mTORC1-mediated signalling
Reactome Imported
Signaling by Notch Reactome Imported
    Subnetwork: A third proteolytic cleavage releases NICD
Reactome Imported
    Subnetwork: Maturation of Notch precursor via proteolytic cleavage
Reactome Imported
    Subnetwork: Mature Notch receptor trafficks to plasma membrane
Reactome Imported
    Subnetwork: NICD trafficks to nucleus
Reactome Imported
    Subnetwork: Notch receptor binds with a ligand
Reactome Imported
    Subnetwork: Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
Reactome Imported
    Subnetwork: Transport of Notch receptor precursor to golgi
Reactome Imported
Signaling by PDGF Reactome Imported
    Subnetwork: Down-stream signal transduction
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: MAP kinase cascade
Reactome Imported
    Subnetwork: MEK activation
Reactome Imported
    Subnetwork: RAF activation
Reactome Imported
    Subnetwork: RAF phosphorylates MEK
Reactome Imported
Signaling by Rho GTPases Reactome Imported
    Subnetwork: Rho GTPase cycle
Reactome Imported
Signaling by TGF beta Reactome Imported
Signaling by VEGF Reactome Imported
    Subnetwork: Neurophilin interactions with VEGF and VEGFR
Reactome Imported
    Subnetwork: VEGF binds to VEGFR leading to receptor dimerization
Reactome Imported
    Subnetwork: VEGF ligand-receptor interactions
Reactome Imported
Signaling by Wnt Reactome Imported
    Subnetwork: Beta-catenin phosphorylation cascade
Reactome Imported
    Subnetwork: Degradation of beta-catenin by the destruction complex
Reactome Imported
Signaling in Immune system Reactome Imported
    Subnetwork: Activated TLR4 signalling
Reactome Imported
    Subnetwork: Activation of C3 and C5
Reactome Imported
    Subnetwork: Activation of the AP-1 family of transcription factors
Reactome Imported
    Subnetwork: Alternative complement activation
Reactome Imported
    Subnetwork: CD28 co-stimulation
Reactome Imported
    Subnetwork: CD28 dependent PI3K/Akt signaling
Reactome Imported
    Subnetwork: CD28 dependent Vav1 pathway
Reactome Imported
    Subnetwork: CREB phosphorylation
Reactome Imported
    Subnetwork: CTLA4 inhibitory signaling
Reactome Imported
    Subnetwork: Classical antibody-mediated complement activation
Reactome Imported
    Subnetwork: Complement cascade
Reactome Imported
    Subnetwork: Costimulation by the CD28 family
Reactome Imported
    Subnetwork: Creation of C4 and C2 activators
Reactome Imported
    Subnetwork: Downstream TCR signaling
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK/MAPK targets
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: ERKs are inactivated
Reactome Imported
    Subnetwork: Generation of second messenger molecules
Reactome Imported
    Subnetwork: Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Reactome Imported
    Subnetwork: Initial triggering of complement
Reactome Imported
    Subnetwork: Innate Immunity Signaling
Reactome Imported
    Subnetwork: Interleukin-1 signaling
Reactome Imported
    Subnetwork: JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Reactome Imported
    Subnetwork: LPS transferred from LBP carrier to CD14
Reactome Imported
    Subnetwork: Lectin pathway of complement activation
Reactome Imported
    Subnetwork: MAP kinases activation in TLR cascade
Reactome Imported
    Subnetwork: MAPK targets/ Nuclear events mediated by MAP kinases
Reactome Imported
    Subnetwork: MyD88 cascade
Reactome Imported
    Subnetwork: PD-1 signaling
Reactome Imported
    Subnetwork: Phosphorylation of CD3 and TCR zeta chains
Reactome Imported
    Subnetwork: Signaling by Interleukins
Reactome Imported
    Subnetwork: TCR signaling
Reactome Imported
    Subnetwork: TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade
Reactome Imported
    Subnetwork: TRAM Cascade
Reactome Imported
    Subnetwork: Terminal pathway of complement
Reactome Imported
    Subnetwork: Toll Like Receptor 10 (TLR10) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 2 Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 3 (TLR3) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 4 (TLR4) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 5 (TLR5) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 7/8 (TLR7/8) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 9 (TLR9) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor TLR1:TLR2 Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor TLR6:TLR2 Cascade
Reactome Imported
    Subnetwork: Toll Receptor Cascades
Reactome Imported
    Subnetwork: Translocation of ZAP-70 to Immunological synapse
Reactome Imported
    Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates RIP1
Reactome Imported
    Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates TBK1/IKK epsilon
Reactome Imported
    Subnetwork: activated TAK1 mediates p38 MAPK activation
Reactome Imported
    Subnetwork: human TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Reactome Imported
Signalling by NGF Reactome Imported
    Subnetwork: AKT phosphorylates targets in the cytosol
Reactome Imported
    Subnetwork: AKT phosphorylates targets in the nucleus
Reactome Imported
    Subnetwork: ARMS-mediated activation
Reactome Imported
    Subnetwork: Activation of TRKA receptors
Reactome Imported
    Subnetwork: Axonal growth inhibition (RHOA activation)
Reactome Imported
    Subnetwork: Axonal growth stimulation
Reactome Imported
    Subnetwork: CREB phosphorylation
Reactome Imported
    Subnetwork: CaM pathway
Reactome Imported
    Subnetwork: CaMK IV-mediated phosphorylation of CREB
Reactome Imported
    Subnetwork: Calmodulin induced events
Reactome Imported
    Subnetwork: Cam-PDE 1 activation
Reactome Imported
    Subnetwork: Cell death signalling via NRAGE, NRIF and NADE
Reactome Imported
    Subnetwork: Ceramide signalling
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK/MAPK targets
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: ERKs are inactivated
Reactome Imported
    Subnetwork: Frs2-mediated activation
Reactome Imported
    Subnetwork: MAP kinase cascade
Reactome Imported
    Subnetwork: MEK activation
Reactome Imported
    Subnetwork: NADE modulates death signalling
Reactome Imported
    Subnetwork: NF-kB is activated and signals survival
Reactome Imported
    Subnetwork: NFG and proNGF binds to p75NTR
Reactome Imported
    Subnetwork: NGF processing
Reactome Imported
    Subnetwork: NGF signalling via TRKA from the plasma membrane
Reactome Imported
    Subnetwork: NGF-independant TRKA activation
Reactome Imported
    Subnetwork: NRAGE signals death through JNK
Reactome Imported
    Subnetwork: NRIF signals cell death from the nucleus
Reactome Imported
    Subnetwork: Negative regulation of the PI3K/AKT network
Reactome Imported
    Subnetwork: Nuclear Events (kinase and transcription factor activation)
Reactome Imported
    Subnetwork: PI3K/AKT signalling
Reactome Imported
    Subnetwork: PKA activation
Reactome Imported
    Subnetwork: PKA-mediated phosphorylation of CREB
Reactome Imported
    Subnetwork: PLC-gamma1 signalling
Reactome Imported
    Subnetwork: Prolonged ERK activation events
Reactome Imported
    Subnetwork: RAF activation
Reactome Imported
    Subnetwork: RAF phosphorylates MEK
Reactome Imported
    Subnetwork: Regulated proteolysis of p75NTR
Reactome Imported
    Subnetwork: Retrograde neurotrophin signalling
Reactome Imported
    Subnetwork: Signalling to ERK5
Reactome Imported
    Subnetwork: Signalling to ERKs
Reactome Imported
    Subnetwork: Signalling to RAS
Reactome Imported
    Subnetwork: Signalling to STAT3
Reactome Imported
    Subnetwork: Signalling to p38 via RIT and RIN
Reactome Imported
    Subnetwork: TRKA activation by NGF
Reactome Imported
    Subnetwork: p38MAPK events
Reactome Imported
    Subnetwork: p75 NTR receptor-mediated signalling
Reactome Imported
    Subnetwork: p75NTR negatively regulates cell cycle via SC1
Reactome Imported
    Subnetwork: p75NTR recruits signalling complexes
Reactome Imported
    Subnetwork: p75NTR regulates axonogenesis
Reactome Imported
    Subnetwork: p75NTR signals via NF-kB
Reactome Imported
Synaptic Transmission Reactome Imported
    Subnetwork: Acetylcholine Binding And Downstream Events
Reactome Imported
    Subnetwork: Acetylcholine Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Activation of AMPA receptors
Reactome Imported
    Subnetwork: Activation of Ca-permeable Kainate Receptor
Reactome Imported
    Subnetwork: Activation of CaMK IV
Reactome Imported
    Subnetwork: Activation of Kainate Receptors upon glutamate binding
Reactome Imported
    Subnetwork: Activation of NMDA receptor upon glutamate binding and postsynaptic events
Reactome Imported
    Subnetwork: Activation of Na-permeable Kainate Receptors
Reactome Imported
    Subnetwork: Activation of Nicotinic Acetylcholine Receptors
Reactome Imported
    Subnetwork: Astrocytic Glutamate-Glutamine Uptake And Metabolism
Reactome Imported
    Subnetwork: CREB phophorylation through the activation of Ras
Reactome Imported
    Subnetwork: CREB phosphorylation through the activation of Adenylate Cyclase
Reactome Imported
    Subnetwork: CREB phosphorylation through the activation of CaMKII
Reactome Imported
    Subnetwork: CREB phosphorylation through the activation of CaMKK
Reactome Imported
    Subnetwork: Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
Reactome Imported
    Subnetwork: Dopamine Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Dopamine clearance from the synaptic cleft
Reactome Imported
    Subnetwork: Electric Transmission Across Gap Junctions
Reactome Imported
    Subnetwork: Enzymatic degradation of Dopamine by monoamine oxidase
Reactome Imported
    Subnetwork: Enzymatic degradation of dopamine by COMT
Reactome Imported
    Subnetwork: Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Reactome Imported
    Subnetwork: Glutamate Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Highly calcium permeable nicotinic acetylcholine receptors
Reactome Imported
    Subnetwork: Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Reactome Imported
    Subnetwork: Highly sodium permeable acetylcholine nicotinic receptors
Reactome Imported
    Subnetwork: Ionotropic activity of Kainate Receptors
Reactome Imported
    Subnetwork: Metabolism of serotonin
Reactome Imported
    Subnetwork: Neuroransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Reactome Imported
    Subnetwork: Neurotransmitter Clearance In The Synaptic Cleft
Reactome Imported
    Subnetwork: Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Neurotransmitter uptake and Metabolism In Glial Cells
Reactome Imported
    Subnetwork: Norepinephrine Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Post NMDA receptor activation events
Reactome Imported
    Subnetwork: Postsynaptic nicotinic acetylcholine receptors
Reactome Imported
    Subnetwork: Presynaptic function of Kainate receptors
Reactome Imported
    Subnetwork: Presynaptic nicotinic acetylcholine receptors
Reactome Imported
    Subnetwork: RSK activation
Reactome Imported
    Subnetwork: Ras activation uopn Ca2+ infux through NMDA receptor
Reactome Imported
    Subnetwork: Serotonin Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Serotonin clearance from the synaptic cleft
Reactome Imported
    Subnetwork: Synthesis of Dopamine
Reactome Imported
    Subnetwork: Trafficking of AMPA receptors
Reactome Imported
    Subnetwork: Trafficking of GluR2-containing AMPA receptors
Reactome Imported
    Subnetwork: Transmission across Chemical Synapses
Reactome Imported
    Subnetwork: Transmission across Electrical Synapses
Reactome Imported
    Subnetwork: Unblocking of NMDA receptor, glutamate binding and activation
Reactome Imported
Transcription Reactome Imported
    Subnetwork: Cleavage of Growing Transcript in the Termination Region
Reactome Imported
    Subnetwork: Formation of RNA Pol II elongation complex
Reactome Imported
    Subnetwork: Formation of the Early Elongation Complex
Reactome Imported
    Subnetwork: Mitochondrial transcription initiation
Reactome Imported
    Subnetwork: Mitochondrial transcription termination
Reactome Imported
    Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE
Reactome Imported
    Subnetwork: RNA Polymerase I Chain Elongation
Reactome Imported
    Subnetwork: RNA Polymerase I Promoter Clearance
Reactome Imported
    Subnetwork: RNA Polymerase I Promoter Escape
Reactome Imported
    Subnetwork: RNA Polymerase I Promoter Opening
Reactome Imported
    Subnetwork: RNA Polymerase I Transcription
Reactome Imported
    Subnetwork: RNA Polymerase I Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase I Transcription Termination
Reactome Imported
    Subnetwork: RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Reactome Imported
    Subnetwork: RNA Polymerase II Pre-transcription Events
Reactome Imported
    Subnetwork: RNA Polymerase II Promoter Escape
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Elongation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Termination
Reactome Imported
    Subnetwork: RNA Polymerase III Abortive And Retractive Initiation
Reactome Imported
    Subnetwork: RNA Polymerase III Chain Elongation
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation From Type 1 Promoter
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation From Type 2 Promoter
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation From Type 3 Promoter
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Termination
Reactome Imported
    Subnetwork: Transcription from mitochondrial promoters
Reactome Imported
Transmembrane transport of small molecules Reactome Imported
    Subnetwork: ABC-family proteins mediated transport
Reactome Imported
    Subnetwork: Amino acid transport across the plasma membrane
Reactome Imported
    Subnetwork: Bicarbonate transporters
Reactome Imported
    Subnetwork: Cation-coupled Chloride cotransporters
Reactome Imported
    Subnetwork: Class II GLUTs
Reactome Imported
    Subnetwork: Facilitative Na+-independent glucose transporters
Reactome Imported
    Subnetwork: Glucose transport
Reactome Imported
    Subnetwork: Hexose transport
Reactome Imported
    Subnetwork: Inositol transporters
Reactome Imported
    Subnetwork: Metal ion SLC transporters
Reactome Imported
    Subnetwork: Multifunctional anion exchangers
Reactome Imported
    Subnetwork: Na+-dependent glucose transporters
Reactome Imported
    Subnetwork: Na+/Cl- dependent neurotransmitter transporters
Reactome Imported
    Subnetwork: Organic anion transport
Reactome Imported
    Subnetwork: Organic anion transporters
Reactome Imported
    Subnetwork: Organic cation transport
Reactome Imported
    Subnetwork: Organic cation/anion/zwitterion transport
Reactome Imported
    Subnetwork: Proton-coupled monocarboxylate transport
Reactome Imported
    Subnetwork: Proton-coupled neutral amino acid transporters
Reactome Imported
    Subnetwork: Proton/oligonucleotide cotransporters
Reactome Imported
    Subnetwork: Regulation of Glucokinase by Glucokinase Regulatory Protein
Reactome Imported
    Subnetwork: Rhesus glycoproteins mediate ammonium transport.
Reactome Imported
    Subnetwork: SLC-mediated transmembrane transport
Reactome Imported
    Subnetwork: Sodium-coupled phosphate cotransporters
Reactome Imported
    Subnetwork: Sodium-coupled sulphate, di- and tri-carboxylate transporters
Reactome Imported
    Subnetwork: Sodium/Calcium exchangers
Reactome Imported
    Subnetwork: Sodium/Proton exchangers
Reactome Imported
    Subnetwork: Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Reactome Imported
    Subnetwork: Transport of inorganic cations/anions and amino acids/oligopeptides
Reactome Imported
    Subnetwork: Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Reactome Imported
    Subnetwork: Transport of nucleotide sugars
Reactome Imported
    Subnetwork: Transport of vitamins, nucleosides, and related molecules
Reactome Imported
    Subnetwork: Type II Na+/Pi cotransporters
Reactome Imported
    Subnetwork: Zinc efflux and compartmentalization by the SLC30 family
Reactome Imported
    Subnetwork: Zinc influx into cells by the SLC39 gene family
Reactome Imported
    Subnetwork: Zinc transporters
Reactome Imported
Xanthine formation Reactome Imported
    Subnetwork: Guanine formation
Reactome Imported
mRNA Processing Reactome Imported
    Subnetwork: C6 deamination of adenosine
Reactome Imported
    Subnetwork: Formation of editosomes by ADAR proteins
Reactome Imported
    Subnetwork: Formation of the Editosome
Reactome Imported
    Subnetwork: Processing of Capped Intron-Containing Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Capped Intronless Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Capped Transcripts
Reactome Imported
    Subnetwork: Processing of Intronless Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP independent Processing of Histone Pre-mRNAs
Reactome Imported
    Subnetwork: Transport of Mature Transcript to Cytoplasm
Reactome Imported
    Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts
Reactome Imported
    Subnetwork: Transport of the SLBP Dependant Mature mRNA
Reactome Imported
    Subnetwork: Transport of the SLBP independent Mature mRNA
Reactome Imported
    Subnetwork: mRNA 3'-end processing
Reactome Imported
    Subnetwork: mRNA Capping
Reactome Imported
    Subnetwork: mRNA Editing
Reactome Imported
    Subnetwork: mRNA Editing: A to I Conversion
Reactome Imported
    Subnetwork: mRNA Editing: C to U Conversion
Reactome Imported
    Subnetwork: mRNA Splicing
Reactome Imported
    Subnetwork: mRNA Splicing - Major Pathway
Reactome Imported
    Subnetwork: mRNA Splicing - Minor Pathway
Reactome Imported

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