Bioinformatics Primers
Pathway Interaction Database provides reviews and commentary illuminating topics of particular interest.
September 2010
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The Laboratory Mouse as a Model System for Human Biology and Disease: An Introduction to the Mouse Genome Informatics (MGI) Database
Original research paper Pathway Interaction Database doi:10.1038/pid.2010.2
The community model organism database for the laboratory mouse, the Mouse Genome Informatics (MGI) database (http://www.informatics.jax.org), integrates diverse genetic and genomic data to facilitate the use of the mouse as a model system for understanding human biology and disease. MGI contains a comprehensive catalog of mouse genes and other genome features that are integrated with manually curated information from the scientific literature and other informatics resources about developmental gene expression, genome variation, gene function, phenotype associations, pathway membership, mammalian orthology and associations with human disease genes. MGI is a unique resource of information on the relationship of mouse models (that is, allelic combinations on specific genetic backgrounds) to human disease.
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Archive
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