Bioinformatics Primers

Pathway Interaction Database provides reviews and commentary illuminating topics of particular interest.

July 2009

• An Introduction to the Human Protein Atlas: Exploration of Protein Profiles in Human Tissues, Cells and Cell Lines

  

  The Human Protein Atlas (http://www.proteinatlas.org) is a publicly available resource for exploration of protein expression profiles in human normal and diseased tissues, cells and cell lines. The profiles are retrieved through immunohistochemistry- and immunofluorescence-based methods, using validated antibodies generated in-house or provided by external collaborators. The protein expression profiles are presented on the Human Protein Atlas, both as aggregated expression values for each included cell type and as high-resolution images. The search options available on the web site allow for combined advanced searches and can be used for identification of potential biomarkers. To date, the Human Protein Atlas contains protein expression profiles for ~33% of the human protein-coding genes.

  Original research paper Pathway Interaction Database doi:10.1038/pid.2009.2