Figure 12b.
From the following article: Understanding environment-disease connections: An introduction to the Comparative Toxicogenomics Database (CTD)
(b) GeneComps. GeneComps provide the 20 genes with the most comparable set of interacting chemicals as the gene subject of the page. Similarity (or comparability) is measured by the Jaccard index, which is calculated as the size of the intersection of interacting chemicals for gene A and gene B divided by the size of the union of those chemicals. Overlapping chemical sets are provided (red arrows). Included here are many genes that are directly activated by ligand-bound AHR or function in the AHR signaling pathway.
