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Figure 1a.


From the following article: An Introduction to the PANTHER Pathway Resource

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Figure 1a
Collapsed phylogenetic tree of a PANTHER protein family. PANTHER protein family PTHR19957, the Syntaxin family, is shown in the PANTHER TreeViewer. The phylogenetic tree was constructed computationally from sequence data. The collapsed tree shows the subfamilies as leaf nodes (blue diamond nodes). Subfamily nodes correspond to common ancestors of extant family members and are annotated, on the basis of experiments performed on extant proteins by expert biologists, with their inferred molecular functions and roles in biological processes and pathways. Each subfamily is represented by a hidden Markov model (HMM) to allow classification of newly discovered protein sequences.